Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/50920
Campo DC Valoridioma
dc.contributor.authorCalbet, Jose A. L.en_US
dc.contributor.authorBoushel, Roberten_US
dc.contributor.otherCalbet, Jose A-
dc.date.accessioned2018-11-24T19:55:37Z-
dc.date.available2018-11-24T19:55:37Z-
dc.date.issued2015en_US
dc.identifier.issn8750-7587en_US
dc.identifier.urihttp://hdl.handle.net/10553/50920-
dc.description.abstractThe accuracy and reproducibility of transpulmonary thermodilution (TPTd) to assess cardiac output (Q˙ ) in exercising men was determined using indocyanine green (ICG) dilution as a reference method. TPTd has been utilized for the assessment of Q˙ and preload indexes of global end-diastolic volume and intrathoracic blood volume, as well as extravascular lung water (EVLW) in resting humans. It remains unknown if this technique is also accurate and reproducible during exercise. Sixteen healthy men underwent catheterization of the right femoral vein (for iced saline injection), an antecubital vein (ICG injection), and femoral artery (thermistor) to determine their Q˙ by TPTd and ICG concentration during incremental one- and two-legged pedaling on a cycle ergometer and combined arm cranking with leg pedaling to exhaustion. There was a close relationship between TPTd-Q˙ and ICG-Q˙ (r 0.95, n 151, standard error of the estimate: 1.452 l/min, P 0.001; mean difference of 0.06 l/min; limits of agreement 2.98 to 2.86 l/min), and TPTd-Q˙ and ICG-Q˙ increased linearly with oxygen uptake with similar intercepts and slopes. Both methods had mean coefficients of variation close to 5% for Q˙ , global end-diastolic volume, and intrathoracic blood volume. The mean coefficient of variation of EVLW, assessed with both indicators (ICG and thermal) was 17% and was sensitive enough to detect a reduction in EVLW of 107 ml when changing from resting supine to upright exercise. In summary, TPTd with bolus injection into the femoral vein is an accurate and reproducible method to assess Q˙ during exercise in humans.en_US
dc.languageengen_US
dc.publisher8750-7587-
dc.relation.ispartofJournal of Applied Physiologyen_US
dc.sourceJournal Of Applied Physiology[ISSN 8750-7587],v. 118 (1), p. 1-10en_US
dc.subject241106 Fisiología del ejercicioen_US
dc.subject.othercardiac outputen_US
dc.subject.otherindocyanineen_US
dc.subject.otherexerciseen_US
dc.subject.otherthermodilutionen_US
dc.subject.otherhumanen_US
dc.titleAssessment of cardiac output with transpulmonary thermodilution during exercise in humansen_US
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.1152/japplphysiol.00686.2014
dc.identifier.scopus84920463516-
dc.identifier.isi000347169000001-
dcterms.isPartOfJournal Of Applied Physiology-
dcterms.sourceJournal Of Applied Physiology[ISSN 8750-7587],v. 118 (1), p. 1-10-
dc.contributor.authorscopusid7004323423-
dc.contributor.authorscopusid7003471688-
dc.description.lastpage10-
dc.description.firstpage1-
dc.relation.volume118-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000347169000001-
dc.contributor.daisngid90295-
dc.contributor.daisngid220476-
dc.identifier.investigatorRIDH-6693-2015-
dc.contributor.wosstandardWOS:Calbet, JAL
dc.contributor.wosstandardWOS:Boushel, R
dc.date.coverdateEnero 2015
dc.identifier.ulpgces
dc.description.sjr1,623
dc.description.jcr3,004
dc.description.sjrqQ2
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Rendimiento humano, ejercicio físico y salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Educación Física-
crisitem.author.orcid0000-0002-9215-6234-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameLópez Calbet, José Antonio-
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