Please use this identifier to cite or link to this item:
Title: Effect of thyroidectomy on bone mineral metabolism. Experimental study in rats
Authors: González Rodríguez, M. D.
Sosa Henríquez, M. 
Limiñana Cañal, Jose Maria 
Bentacor León, P.
UNESCO Clasification: 32 Ciencias médicas
3205 Medicina interna
Keywords: Thyroidectomy
Bone mineral metabolism
Issue Date: 1990
Journal: Anales de Medicina Interna 
Abstract: The aim of the study was to ascertain the importance of calcitonin in the etiopathogenesis of osteoporosis in rats as an animal model. We used 20 female rats on which a thyroidectomy was performed, producing a calcitonin deficit. An autologous transplant of parathyroid gland and replacement therapy of thyroid hormone was carried out. The control group consisted of 20 rats. The levels of parathormone (PTH), calcitonin (CT), osteocalcin (GLA), seric calcium, and density, weight, quantity and mineral bone content of the head of the femur were measured. We found low levels of CT and normal amount of PTH, which contradicted the expected, there was an increment of the mineral bone content, without significant density, quantity and weight changes. We comment on these results.
ISSN: 0212-7199
Source: Anales de medicina interna (Madrid, Spain : 1984)[ISSN 0212-7199],v. 7, p. 500-504 (Enero 1990)
Appears in Collections:Artículos
Show full item record

Page view(s)

checked on Mar 16, 2024

Google ScholarTM



Export metadata

Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.