Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50803
Title: Effect of thyroidectomy on bone mineral metabolism. Experimental study in rats
Authors: González Rodríguez, M. D.
Sosa Henríquez, M. 
Limiñana Cañal, J. M.
Bentacor León, P.
Issue Date: 1990
Publisher: 0212-7199
Journal: Anales de Medicina Interna 
Abstract: The aim of the study was to ascertain the importance of calcitonin in the etiopathogenesis of osteoporosis in rats as an animal model. We used 20 female rats on which a thyroidectomy was performed, producing a calcitonin deficit. An autologous transplant of parathyroid gland and replacement therapy of thyroid hormone was carried out. The control group consisted of 20 rats. The levels of parathormone (PTH), calcitonin (CT), osteocalcin (GLA), seric calcium, and density, weight, quantity and mineral bone content of the head of the femur were measured. We found low levels of CT and normal amount of PTH, which contradicted the expected, there was an increment of the mineral bone content, without significant density, quantity and weight changes. We comment on these results.
URI: http://hdl.handle.net/10553/50803
ISSN: 0212-7199
Source: Anales de medicina interna (Madrid, Spain : 1984)[ISSN 0212-7199],v. 7, p. 500-504
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