Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50793
Title: Bone mineral metabolism in hypercalciuric urolithiasis
Authors: Sosa Henriquez, M. 
Perez Alonso, E. 
Santana Santana, J. R.
Vega Benitez, V.
Domínguez Cabrera, M.
Betancor Leon, P.
UNESCO Clasification: 32 Ciencias médicas
3205 Medicina interna
Keywords: Bone
Mineral metabolism
Hypercalciuric urolithiasis
Issue Date: 1996
Journal: Revista Española de Enfermedades Metabólicas Óseas 
Abstract: Background. To study the possible modifications in bone mineral metabolism: biochemical remodeling markers, calciotropic hormones and bone mass in hypercalciuric patients, and to compare those differences to a control group. Methods. Sixy patients (29 males and 31 females) with hypercalciuria. Formation and Resorption biochemical markers: Alkaline phosphatase, osteocalcin, tartrate resistant acid phosphatase in blood and 24 hours urine excretion of calcium and Hydroxyprolin, calciotropic hormones (Parathormone and Calcitonin) and bone mass by DEXA were also measured. Results were compared to a control group composed by 190 males and 33 females. Results. Hypercalciuric patients had similar bone mass levels than controls, both in the lumbar spine and proximal femur with a good correlation between these two measurements. Bone remodelling biochemical markers of bone formation and resorption remained unchanged. Only with the exception of PTH, which was lower in hypercalciuric patients than in controls. Conclusions. There is no osteopenia in hypercalciuric patients compared to controls. Bone biochemical marcher of formation and resorption remained unchanged. PTH is lower in hypercalciuric patients.
URI: http://hdl.handle.net/10553/50793
ISSN: 1132-8460
Source: Revista Espanola de Enfermedades Metabolicas Oseas[ISSN 1132-8460],v. 5, p. 63-66 (Enero 1996)
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