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Title: Primary cutaneous diffuse large B-cell lymphoma of the leg according to the new WHO-EORTC classification. Two cases
Authors: Hernández-Machín, Buenaventura
Fernández-Misa, Ricardo
Alfonso, Juan L.
Maeso, Ma Carmen
Marrero, Carmen
Borrego, Leopoldo 
UNESCO Clasification: 32 Ciencias médicas
320113 Sifilografía
Keywords: Lymphoma
WHO-EORTC classification
Large B cell
Issue Date: 2005
Journal: Actas dermo-sifiliográficas (Ed. impresa) 
Abstract: Primary cutaneous lymphomas are a heterogeneous group of lymphoproliferative disorders characterized by skin involvement with no evidence of systemic disease at the time of diagnosis. Their clinical behavior is generally indolent, and only occasionally is the development of extracutaneous disease observed. Since the 1980s, primary cutaneous B-cell lymphomas have been considered a specific group of lymphomas, differentiated from both T-cell lymphomas and from secondary cutaneous B-cell lymphomas. Both the EORTC and the WHO have proposed alternative classifications for these entities, with significant discrepancies that were finally resolved through the development of a new classification (WHO-EORTC classification for cutaneous lymphomas), which standardizes criteria that had previously been different. We present two new cases of primary cutaneous diffuse large B-cell lymphoma of the leg according to the new classification.
ISSN: 0001-7310
DOI: 10.1016/S0001-7310(05)73145-8
Source: Actas Dermo-Sifiliograficas[ISSN 0001-7310],v. 96, p. 607-611
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