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Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50575
DC FieldValueLanguage
dc.contributor.authorBenyahia, Samiraen_US
dc.contributor.authorBenayache, Samiren_US
dc.contributor.authorBenayache, Fadilaen_US
dc.contributor.authorQuintana, Jen_US
dc.contributor.authorLópez, Matíasen_US
dc.contributor.authorLeón, Franciscoen_US
dc.contributor.authorHernández, Juan C.en_US
dc.contributor.authorEstevez, Fen_US
dc.contributor.authorBermejo, Jaimeen_US
dc.contributor.otherQuintana, Jose-
dc.contributor.otherEstevez, Francisco-
dc.contributor.otherLeon, Francisco-
dc.contributor.otherBenayache, Fadila-
dc.contributor.otherBenayache, Samir-
dc.date.accessioned2018-11-24T17:07:05Z-
dc.date.available2018-11-24T17:07:05Z-
dc.date.issued2004en_US
dc.identifier.issn0163-3864en_US
dc.identifier.urihttp://hdl.handle.net/10553/50575-
dc.description.abstractIn this paper we report the isolation and structural elucidation of a new flavonoid (1) and three known compounds, 6,8-di-C-methylkaempferol 3-methyl ether (2), oleanolic acid, and 2alpha,3beta-dihydroxyurs-12-en-28-oic acid, from aerial parts of Eucalyptus occidentalis collected in Algeria. Flavonoids 1 and 2 were used to study their biological activities on the human promyelocytic leukemia cell line, HL-60. Our data show that these compounds induce morphological changes and internucleosomal DNA fragmentation characteristic of apoptotic cell death, which is mediated by caspase-8/caspase-3 activation and cytochrome c release.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Natural Productsen_US
dc.sourceJournal Of Natural Products[ISSN 0163-3864],v. 67 (4), p. 527-531en_US
dc.subject32 Ciencias médicasen_US
dc.subject3209 Farmacologíaen_US
dc.subject.otherFlavonoidsen_US
dc.subject.otherLeavesen_US
dc.subject.otherDeathen_US
dc.subject.otherAciden_US
dc.titleIsolation from Eucalyptus occidentalis and Identification of a New Kaempferol Derivative that Induces Apoptosis in Human Myeloid Leukemia Cellsen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1021/np049960fen_US
dc.identifier.scopus2042519322-
dc.identifier.isi000221001000001-
dcterms.isPartOfJournal Of Natural Products-
dcterms.sourceJournal Of Natural Products[ISSN 0163-3864],v. 67 (4), p. 527-531-
dc.contributor.authorscopusid6603316383-
dc.contributor.authorscopusid55887988000-
dc.contributor.authorscopusid6603336437-
dc.contributor.authorscopusid8681043500-
dc.contributor.authorscopusid37018528100-
dc.contributor.authorscopusid57198848400-
dc.contributor.authorscopusid7005039451-
dc.contributor.authorscopusid55205608000-
dc.contributor.authorscopusid7003810011-
dc.contributor.authorscopusid7101636723-
dc.description.lastpage531en_US
dc.description.firstpage527en_US
dc.relation.volume67en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000221001000001-
dc.contributor.daisngid4344889-
dc.contributor.daisngid420505-
dc.contributor.daisngid447236-
dc.contributor.daisngid461918-
dc.contributor.daisngid128315-
dc.contributor.daisngid5158464-
dc.contributor.daisngid32354811-
dc.contributor.daisngid136703-
dc.contributor.daisngid12374093-
dc.contributor.daisngid5955669-
dc.contributor.daisngid384944-
dc.contributor.daisngid5695465-
dc.identifier.investigatorRIDK-5709-2014-
dc.identifier.investigatorRIDK-5125-2014-
dc.identifier.investigatorRIDNo ID-
dc.identifier.investigatorRIDNo ID-
dc.identifier.investigatorRIDNo ID-
dc.description.numberofpages5en_US
dc.utils.revisionSíen_US
dc.contributor.wosstandardWOS:Benyahia, S-
dc.contributor.wosstandardWOS:Benayache, S-
dc.contributor.wosstandardWOS:Benayache, F-
dc.contributor.wosstandardWOS:Quintana, J-
dc.contributor.wosstandardWOS:Lopez, M-
dc.contributor.wosstandardWOS:Leon, F-
dc.contributor.wosstandardWOS:Hernandez, JC-
dc.contributor.wosstandardWOS:Estevez, F-
dc.contributor.wosstandardWOS:Bermejo, J-
dc.date.coverdateAbril 2004en_US
dc.identifier.ulpgcSíen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.jcr2,202-
dc.description.jcrqQ1-
dc.description.scieSCIE-
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Bioquímica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología-
crisitem.author.deptGIR IUIBS: Bioquímica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología-
crisitem.author.orcid0000-0001-8225-4538-
crisitem.author.orcid0000-0002-9728-2774-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameQuintana Aguiar, José Martín-
crisitem.author.fullNameEstévez Rosas, Francisco Jesús-
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