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http://hdl.handle.net/10553/50571
Título: | Cladocalol, a pentacyclic 28-nor-triterpene from Eucalyptus cladocalyx with cytotoxic activity | Autores/as: | Benyahia, Samira Benayache, Samir Benayache, Fadila León, Francisco Quintana, J López, Matías Hernández, Juan C. Estevez, F Bermejo, Jaime |
Clasificación UNESCO: | 32 Ciencias médicas 3209 Farmacología 320907 Fitofármacos |
Palabras clave: | Eucalyptus cladocalyx Myrtaceae Pentacyclic triterpenes Sterol Flavonoid, et al. |
Fecha de publicación: | 2005 | Publicación seriada: | Phytochemistry | Resumen: | A formylated triterpene named cladocalol has been isolated from the leaves of Eucalyptus cladocalyx, together with ursulolactone acetate, ursolic acid, 3 beta-acetate-12,20(29)-lupadien-28-oic acid, beta-sitosterol and the known flavonoid eucalyptine. Their structures were mainly established by extensive NMR studies (H-1 NMR, C-13 NMR, DEPT, H-1-H-1 COSY, HSQC, HMBC) and mass spectroscopy as well as by X-ray crystallographic analysis. In this paper, we report on the cytotoxic effect induced by cladocalol and its derivatives on the myeloid leukemia cell line HL-60. | URI: | http://hdl.handle.net/10553/50571 | ISSN: | 0031-9422 | DOI: | 10.1016/j.phytochem.2004.12.018 | Fuente: | Phytochemistry[ISSN 0031-9422],v. 66 (6), p. 627-632 (Enero 2005) |
Colección: | Artículos |
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