Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50571
Title: Cladocalol, a pentacyclic 28-nor-triterpene from Eucalyptus cladocalyx with cytotoxic activity
Authors: Benyahia, Samira
Benayache, Samir
Benayache, Fadila
León, Francisco
Quintana, J 
López, Matías
Hernández, Juan C.
Estevez, F 
Bermejo, Jaime
UNESCO Clasification: 32 Ciencias médicas
3209 Farmacología
320907 Fitofármacos
Keywords: Eucalyptus cladocalyx
Myrtaceae
Pentacyclic triterpenes
Sterol
Flavonoid, et al
Issue Date: 2005
Journal: Phytochemistry 
Abstract: A formylated triterpene named cladocalol has been isolated from the leaves of Eucalyptus cladocalyx, together with ursulolactone acetate, ursolic acid, 3 beta-acetate-12,20(29)-lupadien-28-oic acid, beta-sitosterol and the known flavonoid eucalyptine. Their structures were mainly established by extensive NMR studies (H-1 NMR, C-13 NMR, DEPT, H-1-H-1 COSY, HSQC, HMBC) and mass spectroscopy as well as by X-ray crystallographic analysis. In this paper, we report on the cytotoxic effect induced by cladocalol and its derivatives on the myeloid leukemia cell line HL-60.
URI: http://hdl.handle.net/10553/50571
ISSN: 0031-9422
DOI: 10.1016/j.phytochem.2004.12.018
Source: Phytochemistry[ISSN 0031-9422],v. 66 (6), p. 627-632 (Enero 2005)
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