Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/50568
Título: A homo-isoflavonoid and a cytotoxic saponin from Dracaena draco
Autores/as: Hernández, Juan C.
León, Francisco
Estevez, F 
Quintana, J 
Bermejo, Jaime
Clasificación UNESCO: 32 Ciencias médicas
24 Ciencias de la vida
2302 Bioquímica
Palabras clave: Steroidal Saponins
Dragons Blood
Hl-60 Cells
Sapogenins
Parts
Fecha de publicación: 2006
Publicación seriada: Chemistry and Biodiversity 
Resumen: Two new compounds, dracol (=(3R)-2,3-dihydro-3,5-dihydroxy-7-methoxy-3-[(4-methoxyphenyl)methyl]-8-methyl-4H-[1]benzopyran-4-one; 1) and icodeside (= (1 beta,3 beta,23S,24S)-3,23-dihydroxy-1-{[2-O(2,3,4-tri-O-acetyl-a-L-rhamnopyranosyl)-a-L-arabinopyranosyl]oxy}spirosta-5,25(27)-dien-24-yl a-L-arabinopyranoside; 2), were isolated from the EtOH extract of the leaves of Dracaena draco, together with 17 known constituents. The structures of 1 and 2 were elucidated by in-depth spectroscopic analysis, and those of the known compounds were identified by comparison of their NMR and MS data with those reported in the literature. Icodeside (2) showed moderate cytotoxicity against human HL-60 and A-431 cells (Table 3).
URI: http://hdl.handle.net/10553/50568
ISSN: 1612-1872
DOI: 10.1002/cbdv.200690008
Fuente: Chemistry & Biodiversity[ISSN 1612-1872],v. 3 (1), p. 62-68
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