Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50568
Title: A homo-isoflavonoid and a cytotoxic saponin from Dracaena draco
Authors: Hernández, Juan C.
León, Francisco
Estevez, F 
Quintana, J 
Bermejo, Jaime
Keywords: Steroidal Saponins
Dragons Blood
Hl-60 Cells
Sapogenins
Parts
Issue Date: 2006
Publisher: 1612-1872
Journal: Chemistry and Biodiversity 
Abstract: Two new compounds, dracol (=(3R)-2,3-dihydro-3,5-dihydroxy-7-methoxy-3-[(4-methoxyphenyl)methyl]-8-methyl-4H-[1]benzopyran-4-one; 1) and icodeside (= (1 beta,3 beta,23S,24S)-3,23-dihydroxy-1-{[2-O(2,3,4-tri-O-acetyl-a-L-rhamnopyranosyl)-a-L-arabinopyranosyl]oxy}spirosta-5,25(27)-dien-24-yl a-L-arabinopyranoside; 2), were isolated from the EtOH extract of the leaves of Dracaena draco, together with 17 known constituents. The structures of 1 and 2 were elucidated by in-depth spectroscopic analysis, and those of the known compounds were identified by comparison of their NMR and MS data with those reported in the literature. Icodeside (2) showed moderate cytotoxicity against human HL-60 and A-431 cells (Table 3).
URI: http://hdl.handle.net/10553/50568
ISSN: 1612-1872
DOI: 10.1002/cbdv.200690008
Source: Chemistry & Biodiversity[ISSN 1612-1872],v. 3 (1), p. 62-68
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