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http://hdl.handle.net/10553/50562
| Título: | A flavonoid with cytotoxic activity and other constituents from Centaurea africana | Autores/as: | Seghiri, Ramdane Boumaza, Ouahiba Mekkiou, Ratiba Benayache, Samir Mosset, Paul Quintana, Jose Estevez, Francisco León, Francisco Bermejo, Jaime Benayache, Fadila |
Clasificación UNESCO: | 32 Ciencias médicas 320907 Fitofármacos |
Palabras clave: | Sesquiterpene Lactones Phenolic-Compounds Aerial Parts Asteraceae Bioassay, et al. |
Fecha de publicación: | 2009 | Publicación seriada: | Phytochemistry Letters | Resumen: | A new acylated flavonoid glucoside named algerianin 1 and a new as natural product, 4'-methyl gossypetin 2, together with 10 known compounds, isovanillic acid ethyl ester, beta-sitosterol, beta-sitosterol 3-O-glucoside, a mixture of alpha and beta-amyrin, 3'-hydroxyflindulatin, chrysoeriol, jaceidin, corniculatusin and centaurein were isolated from the ethanolic extract of the flowering and aerial parts of Centaurea africana Lamk var. africana (Bonnet) M., an endemic species to Algeria and Tunisia collected from El-Kala in the eastern Algeria. The structures were established by chemical and spectral analysis, mainly HREIMS, ESIMS, UV and NMR experiments (GOESY, COSY, ROESY, HSQC and HMBC). Algerianin showed cytotoxicity against the human myeloid leukaemia cell line HL-60. | URI: | http://hdl.handle.net/10553/50562 | ISSN: | 1874-3900 | DOI: | 10.1016/j.phytol.2009.03.002 | Fuente: | Phytochemistry Letters[ISSN 1874-3900],v. 2 (3), p. 114-118 |
| Colección: | Artículos |
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