Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50562
Title: A flavonoid with cytotoxic activity and other constituents from Centaurea africana
Authors: Seghiri, Ramdane
Boumaza, Ouahiba
Mekkiou, Ratiba
Benayache, Samir
Mosset, Paul
Quintana, Jose 
Estevez, Francisco 
León, Francisco
Bermejo, Jaime
Benayache, Fadila
Keywords: Sesquiterpene Lactones
Phenolic-Compounds
Aerial Parts
Asteraceae
Bioassay, et al
Issue Date: 2009
Publisher: 1874-3900
Journal: Phytochemistry Letters 
Abstract: A new acylated flavonoid glucoside named algerianin 1 and a new as natural product, 4'-methyl gossypetin 2, together with 10 known compounds, isovanillic acid ethyl ester, beta-sitosterol, beta-sitosterol 3-O-glucoside, a mixture of alpha and beta-amyrin, 3'-hydroxyflindulatin, chrysoeriol, jaceidin, corniculatusin and centaurein were isolated from the ethanolic extract of the flowering and aerial parts of Centaurea africana Lamk var. africana (Bonnet) M., an endemic species to Algeria and Tunisia collected from El-Kala in the eastern Algeria. The structures were established by chemical and spectral analysis, mainly HREIMS, ESIMS, UV and NMR experiments (GOESY, COSY, ROESY, HSQC and HMBC). Algerianin showed cytotoxicity against the human myeloid leukaemia cell line HL-60. (C) 2009 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
URI: http://hdl.handle.net/10553/50562
ISSN: 1874-3900
DOI: 10.1016/j.phytol.2009.03.002
Source: Phytochemistry Letters[ISSN 1874-3900],v. 2 (3), p. 114-118
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