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Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50560
DC FieldValueLanguage
dc.contributor.authorRomagnoli, Romeoen_US
dc.contributor.authorBaraldi, Pier Giovannien_US
dc.contributor.authorCruz-Lopez, Olgaen_US
dc.contributor.authorPreti, Deliaen_US
dc.contributor.authorBermejo, Jaimeen_US
dc.contributor.authorEstévez, Franciscoen_US
dc.contributor.otherBaraldi, Pier Giovanni-
dc.contributor.otherRomagnoli, Romeo-
dc.contributor.otherEstevez, Francisco-
dc.contributor.otherpreti, delia-
dc.contributor.otherCruz-Lopez, Olga-
dc.date.accessioned2018-11-24T17:00:04Z-
dc.date.available2018-11-24T17:00:04Z-
dc.date.issued2009en_US
dc.identifier.issn1860-7179en_US
dc.identifier.urihttp://hdl.handle.net/10553/50560-
dc.description.abstractA novel series of α-bromoacryloyl N-substituted isatin analogues were found to inhibit the growth and viability of human myeloid leukemia HL-60 and U-937 cells as well as human lymphoid leukemia MOLT-3 cells. These compounds show antiproliferative activity which may be mediated by apoptosis caused by cytochrome c release and caspase activation in human leukemia cells.en_US
dc.languageengen_US
dc.relationDesarrollo de Nuevos, Mas Seguros y Mas Efectivos Compuestos Antileucemicosen_US
dc.relation.ispartofChemMedChemen_US
dc.sourceChemmedchem[ISSN 1860-7179],v. 4 (10), p. 1668-1676en_US
dc.subject32 Ciencias médicasen_US
dc.subject320713 Oncologíaen_US
dc.subject.otherPoly(Adp-Ribose) Polymeraseen_US
dc.subject.otherAnticancer Drugsen_US
dc.subject.otherCancer Cellsen_US
dc.subject.otherDeathen_US
dc.subject.otherCaspasesen_US
dc.subject.otherAgentsen_US
dc.subject.otherCytotoxicityen_US
dc.subject.otherInhibitionen_US
dc.subject.otherMechanismsen_US
dc.subject.otherDiscoveryen_US
dc.titlealpha-Bromoacrylamido N-Substituted Isatin Derivatives as Potent Inducers of Apoptosis in Human Myeloid Leukemia Cellsen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1002/cmdc.200900245en_US
dc.identifier.scopus70349774426-
dc.identifier.isi000270767900012-
dcterms.isPartOfChemmedchem-
dcterms.sourceChemmedchem[ISSN 1860-7179],v. 4 (10), p. 1668-1676-
dc.contributor.authorscopusid7101729609-
dc.contributor.authorscopusid7101681318-
dc.contributor.authorscopusid23093335000-
dc.contributor.authorscopusid6602771700-
dc.contributor.authorscopusid7101636723-
dc.contributor.authorscopusid7003810011-
dc.description.lastpage1676en_US
dc.identifier.issue10-
dc.description.firstpage1668en_US
dc.relation.volume4en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000270767900012-
dc.contributor.daisngid32727-
dc.contributor.daisngid38403-
dc.contributor.daisngid826766-
dc.contributor.daisngid428197-
dc.contributor.daisngid5695465-
dc.contributor.daisngid384944-
dc.identifier.investigatorRIDB-7933-2017-
dc.identifier.investigatorRIDG-9887-2015-
dc.identifier.investigatorRIDK-5125-2014-
dc.identifier.investigatorRIDG-9916-2015-
dc.identifier.investigatorRIDF-3060-2017-
dc.description.numberofpages9en_US
dc.utils.revisionSíen_US
dc.contributor.wosstandardWOS:Romagnoli, R-
dc.contributor.wosstandardWOS:Baraldi, PG-
dc.contributor.wosstandardWOS:Cruz-Lopez, O-
dc.contributor.wosstandardWOS:Preti, D-
dc.contributor.wosstandardWOS:Bermejo, J-
dc.contributor.wosstandardWOS:Estevez, F-
dc.date.coverdateOctubre 2009en_US
dc.identifier.ulpgcSíen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.jcr3,232-
dc.description.jcrqQ1-
dc.description.scieSCIE-
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.project.principalinvestigatorEstévez Rosas, Francisco Jesús-
crisitem.author.deptGIR IUIBS: Bioquímica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología-
crisitem.author.orcid0000-0002-9728-2774-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameEstévez Rosas, Francisco Jesús-
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