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Title: Effect of cigarette smoking on the humoral immune response in pigeon fanciers
Authors: Carrillo, T. 
Rodríguez De Castro, Felipe Carlos B. 
Cuevas, M.
Diaz, F.
Cabrera, P.
UNESCO Clasification: 32 Ciencias médicas
320701 Alergias
Keywords: Chronic bronchitis
Hypersensitivity pneumonitis
Pigeon fanciers
Tobacco smoking
Issue Date: 1991
Journal: Allergy: European Journal of Allergy and Clinical Immunology 
Abstract: Tobacco smoking is associated with increased prevalence of various diseases. In this study, we have used an indirect enzyme-linked immunosorbent assay (ELISA) to investigate the specific IgG response to pigeon serum and its relationship to tobacco smoking. In a large group of pigeon fanciers the development o pigeon breeder's disease and some of the clinical features were also investigated. We found a sensitization rate of 31.9 %, a lower degree than that found by other authors. in spite of using a less specific antigen. We also found that fanciers who are current cigarette smokers had significantly lower levels of IgG antibody to pigeon serum (P < 0.001). Finally, 11.9 % of the population had chronic bronchitis as their only manifestation of possible pigeon-related disease. 19.6 % of the sensitized fanciers had chronic bronchitis, were non-smokers and had no other risk factor for developing chronic bronchitis.
ISSN: 0105-4538
DOI: 10.1111/j.1398-9995.1991.tb00580.x
Source: Allergy[ISSN 0105-4538],v. 46, p. 241-244 (Enero 1991)
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