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Title: Impact of the implementation of a Fracture Liaison Service on pharmaceutical expenses for osteoporosis compared to an area without an FLS
Authors: Naranjo Hernández, Antonio 
Ojeda-Bruno, Soledad
Saavedra, Aida
Molina, Amparo
Negrín Hernández, Miguel Ángel 
UNESCO Clasification: 32 Ciencias médicas
321315 Traumatología
Keywords: Fracture
Pharmaceutical expenditure
Issue Date: 2019
Journal: Expert Review of Pharmacoeconomics and Outcomes Research 
Abstract: Introduction: Fracture Liaison Service (FLS) model for secondary prevention of fractures has demonstrated its cost-effectiveness using decision models. We analyze the impact of a FLS on pharmaceutical expenditures for osteoporosis (OP) in real-world circumstances. Methods: Expenditures on OP medications from January 2011 to January 2017 were compiled. Pharmaceutical expenditures in the southern area of Gran Canaria were used as a control group to measure the impact of implementing an FLS in the northern area. We estimated generalized least squares regressions with interrupted time-series analysis where two interventions were considered: March 2012 (implementation of the FLS) and March 2016 (incorporation of nursing staff for inpatients with hip fracture). Results: The northern area incurred greater expenditures for group I and II drugs. The difference in bisphosphonates expenditures between areas varied from 10.5% higher in the northern area pre-FLS to 11.2% post-FLS and 18.3% since March 2016. However, interrupted time series models do not find a significant impact of implementation of FLS on the pharmaceutical expenditures for either drug group. Conclusion: The implantation of an FLS did not lead to an increase in pharmaceutical expenditures for OP over the 5-year period compared to the standard care provided for secondary fracture preventions.
ISSN: 1473-7167
DOI: 10.1080/14737167.2018.1513791
Source: Expert Review of Pharmacoeconomics and Outcomes Research [ISSN 1473-7167], v. 19 (1), p. 81-87
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