Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/49973
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Del Mar Tavío, María | |
dc.contributor.author | Vila, Jordi | |
dc.contributor.author | Ruiz, Joaquím | |
dc.contributor.author | Amicosante, Gianfranco | |
dc.contributor.author | Franceschini, Nicola | |
dc.contributor.author | Martín-Sánchez, Antonio M. | |
dc.contributor.author | Jiménez De Anta, María Teresa | |
dc.date.accessioned | 2018-11-24T12:14:15Z | - |
dc.date.available | 2018-11-24T12:14:15Z | - |
dc.date.issued | 2000 | |
dc.identifier.issn | 0305-7453 | |
dc.identifier.uri | http://hdl.handle.net/10553/49973 | - |
dc.description.abstract | Ten quinolone-resistant mutants of Citrobacter freundii, which were selected in vitro with fluoroquinolones from two clinical isolates, were studied. The parent isolates were susceptible to quinolones in spite of showing a single substitution in the GyrB (His-417 --> Leu). No change was observed in the outer membrane proteins or in the lipopolysaccharide in any of the ten mutants studied with respect to their parent isolates. The development of quinolone resistance in selected mutants was associated with the appearance of a substitution in the GyrA (Thr-83 --> Ile) in nine of the ten mutants plus enhanced active efflux in all of them. | |
dc.publisher | 0305-7453 | |
dc.relation.ispartof | Journal of Antimicrobial Chemotherapy | |
dc.source | Journal of Antimicrobial Chemotherapy[ISSN 0305-7453],v. 45, p. 521-524 | |
dc.subject.other | Escherichia-Coli | |
dc.subject.other | Mutations | |
dc.title | In vitro selected fluoroquinolone-resistant mutants of Citrobacter freundii: Analysis of the quinolone resistance acquisition | |
dc.type | info:eu-repo/semantics/Article | es |
dc.type | Article | es |
dc.identifier.scopus | 0034114295 | |
dc.identifier.isi | 000086537500016 | |
dc.contributor.authorscopusid | 6701659492 | |
dc.contributor.authorscopusid | 7202012753 | |
dc.contributor.authorscopusid | 35392400000 | |
dc.contributor.authorscopusid | 7006729208 | |
dc.contributor.authorscopusid | 7006270914 | |
dc.contributor.authorscopusid | 7005670807 | |
dc.contributor.authorscopusid | 35412061700 | |
dc.description.lastpage | 524 | |
dc.description.firstpage | 521 | |
dc.relation.volume | 45 | |
dc.type2 | Artículo | es |
dc.contributor.daisngid | 9058102 | |
dc.contributor.daisngid | 24031 | |
dc.contributor.daisngid | 173728 | |
dc.contributor.daisngid | 144499 | |
dc.contributor.daisngid | 651911 | |
dc.contributor.daisngid | 1842149 | |
dc.contributor.daisngid | 459288 | |
dc.contributor.wosstandard | WOS:Tavio, MD | |
dc.contributor.wosstandard | WOS:Vila, J | |
dc.contributor.wosstandard | WOS:Ruiz, J | |
dc.contributor.wosstandard | WOS:Amicosante, G | |
dc.contributor.wosstandard | WOS:Franceschini, N | |
dc.contributor.wosstandard | WOS:Martin-Sanchez, AM | |
dc.contributor.wosstandard | WOS:de Anta, MTJ | |
dc.date.coverdate | Abril 2000 | |
dc.identifier.ulpgc | Sí | es |
item.grantfulltext | none | - |
item.fulltext | Sin texto completo | - |
crisitem.author.dept | Epidemiología y Medicina Preventiva Veterinaria | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Ciencias Clínicas | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.fullName | Tavío Pérez, María Del Mar | - |
crisitem.author.fullName | Martín Sánchez, Antonio Manuel | - |
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