1. accedaCRIS
  2. Publicaciones
  3. Artículos
Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/49973
DC FieldValueLanguage
dc.contributor.authorDel Mar Tavío, Maríaen_US
dc.contributor.authorVila, Jordien_US
dc.contributor.authorRuiz, Joaquímen_US
dc.contributor.authorAmicosante, Gianfrancoen_US
dc.contributor.authorFranceschini, Nicolaen_US
dc.contributor.authorMartín-Sánchez, Antonio M.en_US
dc.contributor.authorJiménez De Anta, María Teresaen_US
dc.date.accessioned2018-11-24T12:14:15Z-
dc.date.available2018-11-24T12:14:15Z-
dc.date.issued2000en_US
dc.identifier.issn0305-7453en_US
dc.identifier.urihttp://hdl.handle.net/10553/49973-
dc.description.abstractTen quinolone-resistant mutants of Citrobacter freundii, which were selected in vitro with fluoroquinolones from two clinical isolates, were studied. The parent isolates were susceptible to quinolones in spite of showing a single substitution in the GyrB (His-417 --> Leu). No change was observed in the outer membrane proteins or in the lipopolysaccharide in any of the ten mutants studied with respect to their parent isolates. The development of quinolone resistance in selected mutants was associated with the appearance of a substitution in the GyrA (Thr-83 --> Ile) in nine of the ten mutants plus enhanced active efflux in all of them.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Antimicrobial Chemotherapyen_US
dc.sourceJournal of Antimicrobial Chemotherapy[ISSN 0305-7453],v. 45, p. 521-524en_US
dc.subject32 Ciencias médicasen_US
dc.subject320103 Microbiología clínicaen_US
dc.subject.otherEscherichia-Colien_US
dc.subject.otherMutationsen_US
dc.titleIn vitro selected fluoroquinolone-resistant mutants of Citrobacter freundii: Analysis of the quinolone resistance acquisitionen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.scopus0034114295-
dc.identifier.isi000086537500016-
dc.contributor.authorscopusid6701659492-
dc.contributor.authorscopusid7202012753-
dc.contributor.authorscopusid35392400000-
dc.contributor.authorscopusid7006729208-
dc.contributor.authorscopusid7006270914-
dc.contributor.authorscopusid7005670807-
dc.contributor.authorscopusid35412061700-
dc.description.lastpage524en_US
dc.description.firstpage521en_US
dc.relation.volume45en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid9058102-
dc.contributor.daisngid24031-
dc.contributor.daisngid173728-
dc.contributor.daisngid144499-
dc.contributor.daisngid651911-
dc.contributor.daisngid1842149-
dc.contributor.daisngid459288-
dc.description.numberofpages4en_US
dc.utils.revisionSíen_US
dc.contributor.wosstandardWOS:Tavio, MD-
dc.contributor.wosstandardWOS:Vila, J-
dc.contributor.wosstandardWOS:Ruiz, J-
dc.contributor.wosstandardWOS:Amicosante, G-
dc.contributor.wosstandardWOS:Franceschini, N-
dc.contributor.wosstandardWOS:Martin-Sanchez, AM-
dc.contributor.wosstandardWOS:de Anta, MTJ-
dc.date.coverdateAbril 2000en_US
dc.identifier.ulpgcSíen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.jcr2,964-
dc.description.jcrqQ1-
dc.description.scieSCIE-
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR Investigación Básica y Aplicada en Ciencias de la Salud-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0002-1808-7461-
crisitem.author.parentorgDepartamento de Ciencias Clínicas-
crisitem.author.fullNameTavío Pérez, María Del Mar-
crisitem.author.fullNameMartín Sánchez, Antonio Manuel-
Appears in Collections:Artículos
Show simple item record

SCOPUSTM   
Citations

14
checked on Nov 17, 2024

WEB OF SCIENCETM
Citations

11
checked on Feb 25, 2024

Page view(s)

93
checked on Nov 16, 2024

Google ScholarTM

Check


Share


Export metadata


Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.