Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/49726
Title: Current level of glycaemic control and its associated factors in patients with type 2 diabetes across Europe: Data from the PANORAMA study
Authors: De Pablos-Velasco, Pedro 
Parhofer, Klaus G.
Bradley, Clare
Eschwège, Eveline
Gönder-Frederick, Linda
Maheux, Pierre
Wood, Ian
Simon, Dominique
Keywords: Insulin Therapy
Glucose Control
Euroaspire-I
Management
Disease, et al
Issue Date: 2014
Publisher: 0300-0664
Journal: Clinical Endocrinology 
Abstract: Objective To provide an update on glycaemic control in European patients with type 2 diabetes based on data from the nine-country, cross-sectional PANORAMA study (NCT00916513).Design Post-hoc analysis to report the number of patients achieving/not achieving glycaemic goal (HbA(1c) < 7%).Patients Patients were randomly or consecutively selected from physician practices in nine countries. Eligible patients were aged 40 years, diagnosed with type 2 diabetes > 1 year prior to study entry, and had an available medical record of > 1 year.Measurements All data were collected at a single visit, including HbA(1c) measurement using a common device (A1CNow((R))). Bivariate and multivariate analyses were used to investigate factors associated with not reaching glycaemic goal.Results Of 5817 patients enrolled (aged 65.9 perpendicular to 10.4 years, 53.7% male), 37.4% had an HbA(1c) >= 7%; (range 25.9% in The Netherlands to 52.0% in Turkey). In adjusted multivariate analyses, higher individual glycaemic target, younger age, poor physician-reported patient adherence to lifestyle/medication, longer diabetes duration, increasing treatment regimen complexity and physician-reported patient's unwillingness to intensify treatment were associated with not achieving goal. However, bivariate analyses also found gender, socioeconomic factors, body mass index, rate of complications and hypoglycaemia to be associated with not achieving goal.Conclusions In PANORAMA, 37.4% of patients enrolled were not at glycaemic goal. Factors relating to patient characteristics, physician selection of individualized HbA(1c) target and diabetes itself (longer duration, more complex treatment) were strongly associated with not achieving goal. Further studies are warranted to explore these associations and evaluate strategies for improving glycaemic control.
URI: http://hdl.handle.net/10553/49726
ISSN: 0300-0664
DOI: 10.1111/cen.12119
Source: Clinical Endocrinology[ISSN 0300-0664],v. 80, p. 47-56
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