Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/49358
Title: Effects of maternal ω-3 supplementation on fatty acids and on visual and cognitive development
Authors: Hurtado, Jose A.
Iznaola, Carmen
Peña, Manuela
Ruíz, Josefa
Peña-Quintana, Luis 
Kajarabille, Naroa
Rodriguez-Santana, Yessica
Sanjurjo, Pablo
Aldámiz-Echevarría, Luis
Ochoa, Julio
Lara-Villoslada, Federico
Keywords: Docosahexaenoic Acid
Neurodevelopmental Outcomes
Dha Supplementation
Infant Development
Premature-Infants, et al
Issue Date: 2015
Publisher: 0277-2116
Journal: Journal of Pediatric Gastroenterology and Nutrition 
Abstract: Objectives: The aim of the present study was to elucidate whether a dairy drink enriched with omega-3 long-chain polyunsaturated fatty acid (LC-PUFA) could have an impact on the lipid profile of the mother and the newborn, and also whether this intervention could affect the newborns' visual and cognitive development.Methods: A total of 110 pregnant women were randomly assigned to one of the following intervention groups: control group (n = 54), taking 400 mL/day of the control dairy drink, and supplemented group (fish oil [FO]) (n = 56), taking 400 mL/day of the fish oil-enriched dairy drink (including similar to 400 mg eicosapentaenoic acid-docosahexaenoic acid [DHA]/day). During the study, the mothers' diets were supervised by a nutritionist to encourage compliance with present recommendations of FA intake. Blood fatty acid profiles were determined in the mother's (at enrollment, at delivery, and at 2.5 and 4 months) and newborn (at delivery and at 2.5 months) placenta and breast milk (colostrum and at 1, 2, and 4 months). Pattern reversal visual evoked potentials (VEPs) (at 2.5 and 7.5 months) and Bayley test (at 12 months) were recorded.Results: DHA percentage was higher in plasma, erythrocyte membranes, and breast milk samples from the FO group. The ratio of nervonic acid was also higher in plasma and erythrocyte lipids of the mother and newborn's blood samples from the FO group. No differences were observed in the Bayley test. No differences were observed in VEPs between both groups. We observed a shorter latency, however, in the lower visual angle (7.5') in the boys of the supplemented group.Conclusions: Omega-3 LC-PUFA dietary supplement during pregnancy and lactation influenced the mother and newborn's fatty acid profile and nervonic acid content but did not show effects on visual and cognitive/psychomotor development.
URI: http://hdl.handle.net/10553/49358
ISSN: 0277-2116
DOI: 10.1097/MPG.0000000000000864
Source: Journal of Pediatric Gastroenterology and Nutrition[ISSN 0277-2116],v. 61, p. 472-480
Appears in Collections:Artículos
Show full item record

SCOPUSTM   
Citations

37
checked on May 9, 2021

WEB OF SCIENCETM
Citations

30
checked on May 9, 2021

Page view(s)

8
checked on May 10, 2021

Google ScholarTM

Check

Altmetric


Share



Export metadata



Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.