Please use this identifier to cite or link to this item:
Title: Comparison of solid phase extraction using micellar desorption combined with LC-FD and LC-MS/MS in the determination of antibiotics fluoroquinolone residues in sewage samples
Authors: Montesdeoca-Esponda, Sarah 
Sosa-Ferrera, Zoraida 
Santana-Rodriguez, José Juan 
UNESCO Clasification: 2301 química analítica
Keywords: Antibiotics
High-performance liquid chromatography
Micellar desorption
Solid-phase extraction, et al
Issue Date: 2012
Publisher: 1082-6076
Project: Desarrollo de Nuevas Estrategias de Extracción en El Análisis de Residuos Farmacéuticos.Implementación en Muestras Reales de Interés Medioambiental. 
Journal: Journal of Liquid Chromatography and Related Technologies 
Abstract: A new “green” methodology, free of hazardous solvents, was developed for the extraction and determination of five fluoroquinolones (levofloxacin, norfloxacin, ciprofloxacin, enrofloxacin, and sarafloxacin) in environmental water matrices. The method is based on solid-phase extraction (SPE) coupled to liquid chromatography (LC) with fluorescence and mass spectrometry detection. In this work, we replaced an organic solvent by a micellar media in the desorption step of the SPE process. This combination has never before been optimized and applied to environmental samples analysis. After SPE extraction optimization, a detailed study on the optimum conditions for micellar desorption (i.e., surfactant type, concentration, and volume) was performed. The proposed method was compared to the conventional SPE procedure using methanol as the desorbing agent and tested on several aqueous environmental samples, including seawater, groundwater, and wastewater. Extraction efficiencies of 73%–97% were obtained for all five compounds with relative standard deviations below 11% in all matrices. Finally, real sewage samples from a hospital and wastewater treatment plant were analyzed with both conventional and micellar desorption using fluorescence and mass spectrometry detection.
ISSN: 1082-6076
DOI: 10.1080/10826076.2011.627622
Source: Journal of Liquid Chromatography and Related Technologies [ISSN 1082-6076], v. 35, p. 2081-2096
Appears in Collections:Artículos
Show full item record


checked on Dec 10, 2023


checked on Jun 5, 2022

Page view(s)

checked on Oct 15, 2022

Google ScholarTM




Export metadata

Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.