|Title:||Childhood underweight, weight gain during childhood to adolescence/young adulthood and incidence of adult metabolic syndrome in the SUN (Seguimiento Universidad de Navarra) Project||Authors:||Pimenta, Adriano M.
Beunza, Juan José
Martinez-Gonzalez, Miguel A.
|UNESCO Clasification:||32 Ciencias médicas
3212 Salud pública
3206 Ciencias de la nutrición
Disease, et al
|Issue Date:||2011||Project:||Red Alimentación Saludable en la Prevención Primaria de Enfermedades Crónicas: la Red Predimed. (Retics 2006)||Journal:||Public Health Nutrition||Abstract:||Objective: To assess associations between childhood body weight, weight gain during childhood to adolescence/young adulthood and incidence of adult metabolic syndrome (MetS).Design: A dynamic prospective cohort study (the SUN Project; Seguimiento Universidad de Navarra). Participants were asked to select which of nine body images most closely represented their body shape at ages 5 and 20 years, and it was used as a proxy of BMI. An incident case of MetS was diagnosed according to criteria of the International Diabetes Federation. Associations between childhood body weight, weight gain during childhood to adolescence/young adulthood and incidence of adult MetS were estimated by multiple-adjusted odds ratios and their 95% confidence intervals.Setting: University of Navarra, Spain.Subjects: The study included 5317 university graduates, followed-up for a median of 6.1 years.Results: The incidence of MetS was 2.9% (1.7% in women and 5.1% in men). Among men, body shape at age 5 years was inversely related to adult MetS (OR = 0.83, 95% CI 0.72, 0.97), whereas weight gain during childhood to adolescence/young adulthood was directly associated with adult MetS (OR = 1.49, 95% CI 1.01, 2.18); both childhood underweight (OR = 5.20, 95% CI 1.87, 14.50) and childhood obesity (OR = 4.66, 95% CI 1.40, 15.51) increased the likelihood of adult MetS. No association was apparent among women.Conclusions: These results support treating childhood underweight and weight gain during childhood to adolescence/young adulthood as part of comprehensive adult MetS prevention efforts in men.||URI:||http://hdl.handle.net/10553/49071||ISSN:||1368-9800||DOI:||10.1017/S1368980010003009||Source:||Public Health Nutrition[ISSN 1368-9800],v. 14, p. 1237-1244 (Julio 2011)|
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