Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/49059
Title: Magnesium intake and depression: The SUN cohort
Authors: Martínez-González, Miguel Ángel
Sánchez-Villegas, Almudena 
UNESCO Clasification: 32 Ciencias médicas
3211 Psiquiatría
Keywords: Self-Reported Diagnosis
Dietary Patterns
Follow-Up
Seguimiento-Universidad
Nutritional Medicine, et al
Issue Date: 2016
Journal: Magnesium Research 
Conference: 14th International Magnesium Symposium - Magnesium and Health 
Abstract: Objective. A higher magnesium intake may reduce the risk of depression. We analyzed this association in the SUN Mediterranean cohort with an expanded sample size (n = 15,836) and a long follow-up (median = 10.2 y). Methods. We followed 9,289 women (age = 34.8, SD = 10.4) and 6,547 men (age = 42.8, SD = 13.1) initially free of any history of depression for a new-onset of medically diagnosed depression (maximum follow-up = 15.9 y). All participants in this cohort were university educated. We systematically reviewed previous studies relating magnesium to depression. Results. We observed 837 incident cases of depression during 147,915 person-years of follow-up in the SUN cohort. No significant association of magnesium intake with the risk of depression was found, with a fully-adjusted hazard ratio = 0.85 (95% confidence interval = 0.60-1.22, for fifth versus first quintile). When we used a more restrictive definition for depression (both a medical diagnosis and habitual use of antidepressants), this HR was 0.63 (0.35-1.14). No significant association was found in our systematic review. Conclusion. No conclusive evidence for an association between magnesium dietary intake and depression incidence was found. Further longitudinal studies with a larger sample size and a better assessment of confounders and of depression cases are needed to try to identify potential protection against depression by magnesium.
URI: http://hdl.handle.net/10553/49059
ISSN: 0953-1424
DOI: 10.1684/mrh.2016.0409
Source: Magnesium Research[ISSN 0953-1424],v. 29, p. 102-111 (Septiembre 2016)
Appears in Collections:Artículos
Show full item record

SCOPUSTM   
Citations

9
checked on Jun 26, 2022

WEB OF SCIENCETM
Citations

9
checked on Jun 26, 2022

Page view(s)

15
checked on Apr 30, 2022

Google ScholarTM

Check

Altmetric


Share



Export metadata



Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.