Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/48776
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dc.contributor.authorVázquez-Polo, F. J.
dc.contributor.authorNegrín-Hernández, M. A.
dc.date.accessioned2018-11-24T00:49:54Z-
dc.date.available2018-11-24T00:49:54Z-
dc.date.issued2004
dc.identifier.issn1696-2281
dc.identifier.urihttp://hdl.handle.net/10553/48776-
dc.description.abstractMost published research on the comparison between medical treatment options merely compares the results (effectiveness and cost) obtained for each treatment group. The present work proposes the incorporation of other patient characteristics into the analysis. Most of the studies carried out in this context assume normality of both costs and effectiveness. In practice, however, the data are not always distributed according to this assumption. Altervative models have to be developed. In this paper, we present a general model of cost-effectiveness, incorporating both binary effectiveness and skewed cost. In a practical application, we compare two highly active antiretroviral treatments applied to asymptomatic HIV patients. We propose a logit model when the effectiveness is measured depending on whether an initial purpose is achieved. For this model, the measure to compare treatments is the difference in the probability of success. Besides, the cost data usually present a right skewing. We propose the use of the log-transformation to carry out the regression model. The three models are fitted demonstrating the advantages of this modelling. The cost-effectiveness acceptability curve is used as a measure for decision-making.
dc.publisher1696-2281
dc.relation.ispartofSORT
dc.sourceSORT[ISSN 1696-2281],v. 28, p. 87-108
dc.titleIncorporating patients' characteristics in cost-effectiveness studies with clinical trial data: A flexible Bayesian approach
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.scopus17144439118
dc.contributor.authorscopusid6602318225
dc.contributor.authorscopusid8607491000
dc.description.lastpage108
dc.description.firstpage87
dc.relation.volume28
dc.type2Artículoes
dc.date.coverdateEnero 2004
dc.identifier.ulpgces
dc.description.sellofecytSello FECYT
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR TIDES- Técnicas estadísticas bayesianas y de decisión en la economía y empresa-
crisitem.author.deptIU de Turismo y Desarrollo Económico Sostenible-
crisitem.author.deptDepartamento de Métodos Cuantitativos en Economía y Gestión-
crisitem.author.deptGIR TIDES- Técnicas estadísticas bayesianas y de decisión en la economía y empresa-
crisitem.author.deptIU de Turismo y Desarrollo Económico Sostenible-
crisitem.author.deptDepartamento de Métodos Cuantitativos en Economía y Gestión-
crisitem.author.orcid0000-0002-0632-6138-
crisitem.author.orcid0000-0002-7074-6268-
crisitem.author.parentorgIU de Turismo y Desarrollo Económico Sostenible-
crisitem.author.parentorgIU de Turismo y Desarrollo Económico Sostenible-
crisitem.author.fullNameVázquez Polo, Francisco José-
crisitem.author.fullNameNegrín Hernández, Miguel Ángel-
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