Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/48764
Title: Comparing meta-analyses for chronic obstructive pulmonary disease
Authors: Vázquez-Polo, Francisco José 
Moreno, Elías
Negrín, Miguel Angel 
Girón, Francisco Javier
Martínez, María Lina
Issue Date: 2011
Publisher: 1473-7167
Journal: Expert Review of Pharmacoeconomics and Outcomes Research 
Abstract: In the paper by Oppe et al., a cost-effectiveness analysis of alternative treatments for chronic obstructive pulmonary disease (COPD), based on data from four different trials, is considered. The goal is to compare the usual (frequentist and Bayesian) fixed-effects (FE) and random-effects (RE) normal model for carrying out meta-analysis. Under RE and FE models, the meta-estimation of some quantities of interest for the disease are also carried out using three out of the four trials, and afterwards data from the fourth are incorporated into the meta-estimation. From these sequential estimators, some conclusions on the FE and RE procedures are drawn. Furthermore, as far as the cost-effectiveness is concerned, the main conclusion of the paper is that the Bayesian RE procedure overrides the Bayesian FE and frequentist methods for cost-effectiveness meta-analysis.
URI: http://hdl.handle.net/10553/48764
ISSN: 1473-7167
DOI: 10.1586/erp.11.31
Source: Expert Review of Pharmacoeconomics and Outcomes Research[ISSN 1473-7167],v. 11, p. 277-279
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