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Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/48252
DC FieldValueLanguage
dc.contributor.authorRosquete, Laura I.en_US
dc.contributor.authorCabrera-Serra, M. Gabrielaen_US
dc.contributor.authorPiñero, José E.en_US
dc.contributor.authorMartin-Rodriguez, Patriciaen_US
dc.contributor.authorFernández-Pérez, Leandroen_US
dc.contributor.authorLuis, Javier G.en_US
dc.contributor.authorMcNaughton-Smith, Granten_US
dc.contributor.authorAbad-Grillo, Teresaen_US
dc.contributor.otherDiaz-Chico, Juan-
dc.contributor.otherPatricia, Martin Rodriguez-
dc.contributor.otherFernandez-Perez, Leandro-
dc.contributor.otherAbad Grillo, Teresa-
dc.contributor.otherPinero, Jose-
dc.date.accessioned2018-11-23T20:10:07Z-
dc.date.available2018-11-23T20:10:07Z-
dc.date.issued2010en_US
dc.identifier.issn0968-0896en_US
dc.identifier.urihttp://hdl.handle.net/10553/48252-
dc.description.abstractA set of derivatives encompassing structural modifications on the privileged phenalenone scaffold were assessed for their antiparasitic activities against the most clinically relevant forms of trypanosomiasis and leishmaniasis. Several compounds exhibited leishmanicidal effects at levels comparable or better than the reference drug pentamidine, while the parent phenalenone was shown to have a level of activity against Trypanosoma cruzi comparable to the marketed drug benznidazole.en_US
dc.languageengen_US
dc.relation.ispartofBioorganic and Medicinal Chemistryen_US
dc.sourceBioorganic & Medicinal Chemistry[ISSN 0968-0896],v. 18 (12), p. 4530-4534en_US
dc.subject32 Ciencias médicasen_US
dc.subject230207 Química clínicaen_US
dc.subject.otherMagnesium Exchange-Reactionen_US
dc.subject.otherMusa-Acuminataen_US
dc.subject.otherSinglet Oxygenen_US
dc.subject.otherAte Complexen_US
dc.subject.otherPhytoalexinsen_US
dc.subject.otherLeishmaniasisen_US
dc.subject.other9-Phenylphenalenonesen_US
dc.subject.otherChemotherapyen_US
dc.titleSynthesis and in vitro antiprotozoal evaluation of substituted phenalenone analoguesen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.bmc.2010.04.062en_US
dc.identifier.scopus77953139020-
dc.identifier.isi000278480900039-
dcterms.isPartOfBioorganic & Medicinal Chemistry-
dcterms.sourceBioorganic & Medicinal Chemistry[ISSN 0968-0896],v. 18 (12), p. 4530-4534-
dc.contributor.authorscopusid36020652000-
dc.contributor.authorscopusid16027764800-
dc.contributor.authorscopusid7006711532-
dc.contributor.authorscopusid36604772400-
dc.contributor.authorscopusid6506777525-
dc.contributor.authorscopusid7006391384-
dc.contributor.authorscopusid6506992702-
dc.contributor.authorscopusid57194376958-
dc.description.lastpage4534en_US
dc.description.firstpage4530en_US
dc.relation.volume18en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000278480900039-
dc.contributor.daisngid23858890-
dc.contributor.daisngid6038638-
dc.contributor.daisngid207831-
dc.contributor.daisngid3922169-
dc.contributor.daisngid795544-
dc.contributor.daisngid267487-
dc.contributor.daisngid2131744-
dc.contributor.daisngid1534461-
dc.identifier.investigatorRIDH-1527-2015-
dc.identifier.investigatorRIDH-3238-2015-
dc.identifier.investigatorRIDH-1493-2015-
dc.identifier.investigatorRIDO-4478-2017-
dc.identifier.investigatorRIDNo ID-
dc.description.numberofpages5en_US
dc.utils.revisionSíen_US
dc.contributor.wosstandardWOS:Rosquete, LI-
dc.contributor.wosstandardWOS:Cabrera-Serra, MG-
dc.contributor.wosstandardWOS:Pinero, JE-
dc.contributor.wosstandardWOS:Martin-Rodriguez, P-
dc.contributor.wosstandardWOS:Fernandez-Perez, L-
dc.contributor.wosstandardWOS:Luis, JG-
dc.contributor.wosstandardWOS:McNaughton-Smith, G-
dc.contributor.wosstandardWOS:Abad-Grillo, T-
dc.date.coverdateJunio 2010en_US
dc.identifier.ulpgcSíen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.jcr2,978-
dc.description.jcrqQ2-
dc.description.scieSCIE-
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Farmacología Molecular y Traslacional-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUIBS: Farmacología Molecular y Traslacional-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0002-2378-3242-
crisitem.author.orcid0000-0001-7802-465X-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameMartín Rodríguez, Patricia-
crisitem.author.fullNameFernández Pérez, Leandro Francisco-
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