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http://hdl.handle.net/10553/48251
| Title: | Cytotoxic triterpenoids from Maytenus retusa | Authors: | Oramas-Royo, Sandra M. Chávez, Haydee Martin-Rodriguez, Patricia Fernández-Pérez, Leandro Ravelo, Ángel G. Estévez-Braun, Ana |
UNESCO Clasification: | 32 Ciencias médicas 2302 Bioquímica |
Keywords: | Quinone-Methide Triterpenes Absolute-Configuration Species Celastraceae Revised Structure Natural-Products, et al |
Issue Date: | 2010 | Publisher: | 0163-3864 | Project: | Estudios de Nuevos Moduladores de Las Actividades de Stat y de Los Receptores Para Estrogenos: Potencial Aplicacion Como Antitumorales | Journal: | Journal of Natural Products | Abstract: | Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by ID and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC50 values ranging between 0.2 and 4.7 mu M. | URI: | http://hdl.handle.net/10553/48251 | ISSN: | 0163-3864 | DOI: | 10.1021/np100517u | Source: | Journal Of Natural Products[ISSN 0163-3864],v. 73 (12), p. 2029-2034 |
| Appears in Collections: | Artículos |
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