Injection effect on the sensitivity in an isothermal titration calorimeter

Abstract

By using electrical calibrations and with the injection of liquids with very different heating capacities (water and cyclohexane), it is made a thorough evaluation of the ‘injection effect’ in terms of the parameter ρc p f (ρc p – volumetric heat capacity, f – injection flow) in an isothermal titration calorimeter. This effect can be evaluated accurately in the case of non-volatile liquids, however, when dealing with volatile liquids, the uncertainty in their determination increases because of the vaporization heat.