Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/48035
Título: Vincristine impairs platelet aggregation in dogs with lymphoma
Autores/as: Grau-Bassas, Enrique Rodriguez 
Kociba, Gary J.
Couto, C. Guillermo
Palabras clave: Thrombocytopenia
Fecha de publicación: 2000
Editor/a: 0891-6640
Publicación seriada: Journal of Veterinary Internal Medicine 
Resumen: Platelet aggregation before and after administration of 0.5 mg/m(2) of vincristine (VCR) was evaluated in 7 dogs with spontaneously occuring lymphoma. Aggregation on platelet-rich plasma separated from blood collected in 3.8% sodium citrate was performed using adenosine diphosphate (ADP), arachidonic acid (AA), and collagen (COL) as agonists. The slope for aggregation in response to ADP was significantly lower after administration of VCR (P = .032). Maximal aggregation after administration of VCR was significantly lower in response to ADP, COL, and AA (P = .03, P = .04, and P = .03, respectively).
URI: http://hdl.handle.net/10553/48035
ISSN: 0891-6640
DOI: 10.1111/j.1939-1676.2000.tb01503.x
Fuente: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine[ISSN 0891-6640],v. 14, p. 81-85
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