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Title: Effects of a reputed immunostimulant on the innate immune system of goat kids
Authors: Morales-delaNuez, A.
Castro, N. 
Moreno-Indias, I.
Juste, M. C. 
Sánchez-Macías, D.
Briggs, H.
Capote, J. 
Argüello, A. 
Keywords: Inflammatory Challenge
Passive Transfer
Sheep, et al
Issue Date: 2009
Publisher: 0921-4488
Journal: Small Ruminant Research 
Abstract: Forty newborn Majorera goats were randomly assigned to one of two groups. On the first day of life, the kids were fed atomized colostrum. The kids were subsequently fed a milk replacer (16% w/v) twice a day. The experimental group received two intramuscular doses of a reputed immunostimulant composed of a Propionibacterium acnes extract, Ochrobactrum intermedium lipopolysaccharides, and Proclin (R) at 10 and 40 days of age, whereas, the control group received two doses of saline solution. Blood samples were collected weekly from kids age 10 to 66 days postpartum to measure the total and differential white blood cell counts, the plasma IgG, IgA, and IgM levels, and the activities of the total and the alternative complement systems. The white blood cell and the differential cell counts were the same for both groups. No statistical differences were found for the plasma IgG, IgA, and IgM concentrations. Complement system activity Was undetectable in both groups. Summarizing, the reputed immunostimulant did not affect the immune system of goats. Thus, veterinarians should carefully consider whether it is prudent to recommended this kind of product. because while it increases farmers' expenses it apparently does not improve the state of the innate immune system of the neonatal goat. (C) 2009 Elsevier B.V. All rights reserved.
ISSN: 0921-4488
DOI: 10.1016/j.smallrumres.2009.06.016
Source: Small Ruminant Research[ISSN 0921-4488],v. 85, p. 23-26
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