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Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47720
DC FieldValueLanguage
dc.contributor.authorSantana-Rodríguez, Norbertoen_US
dc.contributor.authorLlontop, Pedroen_US
dc.contributor.authorClavo, Bernardinoen_US
dc.contributor.authorCamacho, Rafaelen_US
dc.contributor.authorQuintana, Ardielen_US
dc.contributor.authorFiuza, María D.en_US
dc.contributor.authorGarcía-Castellano, José Manuelen_US
dc.contributor.authorPonce-González, Miguel A.en_US
dc.contributor.authorZerecero, Keilaen_US
dc.contributor.authorFernández-Pérez, Leandroen_US
dc.contributor.authorBrito-Godoy, Yaniraen_US
dc.contributor.authorRuíz-Caballero, José A.en_US
dc.date.accessioned2018-11-23T15:51:36Z-
dc.date.available2018-11-23T15:51:36Z-
dc.date.issued2013en_US
dc.identifier.issn0022-4804en_US
dc.identifier.urihttp://hdl.handle.net/10553/47720-
dc.description.abstractBackground: Necrosis of the bronchial stump is a very important trigger for bronchopleural fistula. The administration of local autologous platelet-poor plasma (PPP) could protect the bronchial stump.Materials and methods: Left pneumonectomy was performed in 25 Sprague-Dawley rats. Animals were randomly assigned to a control group (n = 13) and PPP group (n = 12). PPP was locally administered on the bronchial stump after pneumonectomy. We analyzed histologic changes in the bronchial stump and messenger RNA expression changes of genes involved in wound repair at 10 and 20 d.Results: Local PPP treatment produced a mass of fibrous tissue surrounding the bronchial stump and significantly decreased the presence of necrosis at 20 d. PPP increased the expression of insulin like growth factor 1 at 10 d although it did not reach statistical significance.Conclusions: Our findings indicate that local PPP treatment of the bronchial stump after pneumonectomy decreased necrosis and could have a protective effect on the bronchial stump.en_US
dc.languageengen_US
dc.relationEstudio Funcional y Molecular de Las Proteínas Socs en Un Modelo de Resistencia Hepática A Insulina.en_US
dc.relation.ispartofJournal of Surgical Researchen_US
dc.sourceJournal of Surgical Research[ISSN 0022-4804],v. 183, p. 68-74en_US
dc.subject32 Ciencias médicasen_US
dc.subject3213 Cirugíaen_US
dc.subject.otherRich Plasmaen_US
dc.subject.otherGrowth-Factorsen_US
dc.subject.otherFibrin Glueen_US
dc.titleAutologous platelet-poor plasma decreases the bronchial stump necrosis in raten_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.jss.2012.12.039en_US
dc.identifier.scopus84879075597-
dc.identifier.isi000320599600012-
dc.contributor.authorscopusid56072780900-
dc.contributor.authorscopusid37041705700-
dc.contributor.authorscopusid57190093030-
dc.contributor.authorscopusid7005843759-
dc.contributor.authorscopusid55597933900-
dc.contributor.authorscopusid56698082300-
dc.contributor.authorscopusid6602732739-
dc.contributor.authorscopusid57192669803-
dc.contributor.authorscopusid8589373600-
dc.contributor.authorscopusid42762455500-
dc.contributor.authorscopusid6506777525-
dc.contributor.authorscopusid42761012500-
dc.contributor.authorscopusid6602240153-
dc.description.lastpage74en_US
dc.description.firstpage68en_US
dc.relation.volume183en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid1685892-
dc.contributor.daisngid3257911-
dc.contributor.daisngid777033-
dc.contributor.daisngid3732849-
dc.contributor.daisngid9113362-
dc.contributor.daisngid1466032-
dc.contributor.daisngid2034496-
dc.contributor.daisngid7076641-
dc.contributor.daisngid8027638-
dc.contributor.daisngid795544-
dc.contributor.daisngid20670966-
dc.contributor.daisngid3685092-
dc.description.numberofpages7en_US
dc.utils.revisionSíen_US
dc.contributor.wosstandardWOS:Santana-Rodriguez, N-
dc.contributor.wosstandardWOS:Llontop, P-
dc.contributor.wosstandardWOS:Clavo, B-
dc.contributor.wosstandardWOS:Camacho, R-
dc.contributor.wosstandardWOS:Quintana, A-
dc.contributor.wosstandardWOS:Fiuza, MD-
dc.contributor.wosstandardWOS:Garcia-Castellano, JM-
dc.contributor.wosstandardWOS:Ponce-Gonzalez, MA-
dc.contributor.wosstandardWOS:Zerecero, K-
dc.contributor.wosstandardWOS:Fernandez-Perez, L-
dc.contributor.wosstandardWOS:Brito-Godoy, Y-
dc.contributor.wosstandardWOS:Ruiz-Caballero, JA-
dc.date.coverdateJulio 2013en_US
dc.identifier.ulpgcSíen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr0,874-
dc.description.jcr2,121-
dc.description.sjrqQ1-
dc.description.jcrqQ2-
dc.description.scieSCIE-
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.project.principalinvestigatorFernández Pérez, Leandro Francisco-
crisitem.author.deptGIR IUIBS: Farmacología Molecular y Traslacional-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptGIR IUIBS: Farmacología Molecular y Traslacional-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0003-2522-1064-
crisitem.author.orcid0000-0001-7802-465X-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameClavo Varas,Bernardino-
crisitem.author.fullNameFernández Pérez, Leandro Francisco-
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