Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47543
Title: Relationship between rheumatoid arthritis and Mycoplasma pneumoniae: A case-control study
Authors: Ramírez Corbera, Ana Sofía 
Rosas, Alexis
Hernández Beriain, José Ángel 
Orengo Valverde, J. C.
Saavedra Santana, Pedro 
De la Fé Rodríguez, Christian
Fernández Rodríguez, Antonio Jesús 
Poveda Guerrero, José Bismarck 
UNESCO Clasification: 3207 Patología
320714 Osteopatología
Keywords: Synovial-Fluid Samples
Ureaplasma-Urealyticum
Inflammatory Arthritides
Septic Arthritis
Fermentans, et al
Issue Date: 2005
Publisher: 1462-0324
Journal: Rheumatology 
Abstract: Objective. Rheumatoid arthritis (RA) has a complex and multifactorial aetiology. Infectious agents could start this disease. The majority of the characteristics of this infirmity can be observed in chronic arthritis produced by mycoplasmas in animals. In this study the association between Mycoplasma pneumoniae and RA has been evaluated.Methods. A case-control study was performed. Sera taken from 78 RA patients and from 156 controls were analysed to ascertain the levels of immunoglobulin G (IgG) against M. pneumoniae. Other variables, like age, gender, work status, history of pneumonia, etc., were recorded in a questionnaire.Results. The presence of antibodies against M. pneumoniae was associated with RA (odds ratio=2.34, P < 0.001).Conclusions. The results suggest that M. pneumoniae could be a cofactor in the pathogenesis of RA; however, more studies need to be done.
URI: http://hdl.handle.net/10553/47543
ISSN: 1462-0324
DOI: 10.1093/rheumatology/keh630
Source: Rheumatology [ISSN 1462-0324], v. 44 (7), p. 912-914
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