|Title:||Virulence factors and pathogenicity of Hafnia alvei for gilthead seabream, Sparus aurata L||Authors:||Padilla, D.
Real Valcárcel, Fernando
Rainbow-Trout, et al
|Issue Date:||2005||Publisher:||0140-7775||Journal:||Journal of Fish Diseases||Abstract:||Virulence factors (eae gene, haemolytic capacity, fimbriae, resistance to the bactericidal effect of serum, siderophore production) and pathogenicity for gilthead seabream, Sparus aurata L., were analysed for 23 Hafnia alvei strains. None of the strains used in LD50 studies were lethal for seabream at doses as high as > 10(8) cfu mL(-1). In chronic challenge studies differences in severity of the inflammatory response were observed between strains. On the basis of correlation of the inflammatory response to different strains of H. alvei in seabream with those virulence factors studied, it was only possible to establish a positive correlation between pathogenicity and resistance to the bactericidal effect of fish serum. Gilthead seabream is thus a species with considerable resistance to experimental infection with H. alvei. The bacterium does, however, have the capacity to remain viable in seabream for up to 3 months, without any clinical signs. Hafnia alvei is a well-recognized human and animal pathogen. Thus, as the pathogen can coexist with aquaculture operations, cultured gilthead seabream could represent a risk to human health as a carrier in some circumstances.||URI:||http://hdl.handle.net/10553/47252||ISSN:||0140-7775||DOI:||10.1111/j.1365-2761.2005.00643.x||Source:||Journal Of Fish Diseases[ISSN 0140-7775],v. 28 (7), p. 411-417|
|Appears in Collections:||Artículos|
checked on Jul 25, 2021
WEB OF SCIENCETM
checked on May 23, 2021
checked on Jul 17, 2021
Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.