Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10553/47222
Campo DC | Valor | idioma |
---|---|---|
dc.contributor.author | El Aamri, F. | - |
dc.contributor.author | Real Valcárcel, Fernando | - |
dc.contributor.author | Acosta, F. | - |
dc.contributor.author | Bravo García, Jimena | - |
dc.contributor.author | Román, L. | - |
dc.contributor.author | Déniz, S. | - |
dc.contributor.author | Padilla Castillo, Daniel Fermín | - |
dc.date.accessioned | 2018-11-23T11:48:43Z | - |
dc.date.available | 2018-11-23T11:48:43Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1050-4648 | - |
dc.identifier.uri | http://hdl.handle.net/10553/47222 | - |
dc.description.abstract | Streptococcus iniae is a Gram-positive bacteria that causes invasive infections with severe septicemia and meningitis, producing high economic losses in marine and continental aquaculture. Head kidney leukocytes of European sea bass (Dicentrarchus labrax) were used to measure the differential innate immune response upon infection with S. iniae. The complete inhibition in the production of intracellular superoxide radicals and total peroxidase content was observed in infected cells. This study also elucidates changes in the relative expression of some immune-related genes. Interleukin 1 beta, tumor necrosis factor-a and interleukin-6 reached a peak of expression at 4-8 h post-infection, subsequently decreasing significantly up to 48 h post-infection. However, interleukin-10 and Mx protein increased over time, reaching the pick of expression at 48 h post-infection, whereas caspase-3 showed down regulation until 48 h post-infection. The in vivo study of immune related genes show the same kinetics of mRNAs expression as in vitro experience. The proinflammatory cytokines mRNA transcription levels peaked at an earlier time in vivo than in vitro system. Our findings indicate that there is a direct relationship between the dissemination of bacteria and the resulting infection-associated inhibition of respiratory burst, apoptosis, and the pro- and anti-inflammatory gene expression profiles. (C) 2015 Published by Elsevier Ltd. | - |
dc.language | eng | - |
dc.publisher | 1050-4648 | - |
dc.relation.ispartof | Fish and Shellfish Immunology | - |
dc.source | Fish and Shellfish Immunology[ISSN 1050-4648],v. 46, p. 436-441 | - |
dc.subject | 310905 Microbiología | - |
dc.subject.other | Salmo-Salar L. | - |
dc.subject.other | Atlantic Salmon | - |
dc.subject.other | Rainbow-Trout | - |
dc.subject.other | Measure Degranulation | - |
dc.subject.other | Expression Analysis | - |
dc.subject.other | Respiratory Burst | - |
dc.subject.other | Molecular-Cloning | - |
dc.subject.other | Adaptive Immunity | - |
dc.subject.other | Direct Assay | - |
dc.subject.other | Fish | - |
dc.title | Differential innate immune response of European seabass (Dicentrarchus labrax) against Streptococcus iniae | - |
dc.type | info:eu-repo/semantics/Article | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.fsi.2015.05.054 | - |
dc.identifier.pmid | 26099220 | - |
dc.identifier.scopus | 84938066597 | - |
dc.identifier.isi | 000363071200031 | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | 0000-0002-1098-7529 | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.authorscopusid | 55351966600 | - |
dc.contributor.authorscopusid | 7005397318 | - |
dc.contributor.authorscopusid | 56269311600 | - |
dc.contributor.authorscopusid | 23059544100 | - |
dc.contributor.authorscopusid | 50661926900 | - |
dc.contributor.authorscopusid | 7003859353 | - |
dc.contributor.authorscopusid | 7005088705 | - |
dc.description.lastpage | 441 | - |
dc.identifier.issue | 2 | - |
dc.description.firstpage | 436 | - |
dc.relation.volume | 46 | - |
dc.investigacion | Ciencias de la Salud | - |
dc.type2 | Artículo | - |
dc.contributor.daisngid | 3017971 | - |
dc.contributor.daisngid | 32158446 | - |
dc.contributor.daisngid | 878226 | - |
dc.contributor.daisngid | 1844262 | - |
dc.contributor.daisngid | 16153744 | - |
dc.contributor.daisngid | 28148410 | - |
dc.contributor.daisngid | 1039753 | - |
dc.utils.revision | Sí | - |
dc.contributor.wosstandard | WOS:El Aamri, F | - |
dc.contributor.wosstandard | WOS:Real, F | - |
dc.contributor.wosstandard | WOS:Acosta, F | - |
dc.contributor.wosstandard | WOS:Bravo, J | - |
dc.contributor.wosstandard | WOS:Roman, L | - |
dc.contributor.wosstandard | WOS:Deniz, S | - |
dc.contributor.wosstandard | WOS:Padilla, D | - |
dc.date.coverdate | Octubre 2015 | - |
dc.identifier.ulpgc | Sí | - |
dc.contributor.buulpgc | BU-VET | - |
dc.description.sjr | 1,268 | - |
dc.description.jcr | 3,025 | - |
dc.description.sjrq | Q1 | - |
dc.description.jcrq | Q1 | - |
dc.description.scie | SCIE | - |
item.fulltext | Sin texto completo | - |
item.grantfulltext | none | - |
crisitem.author.dept | GIR IUSA-ONE HEALTH 2 - Sanidad Animal de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas y Seguridad Alimentaria | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.dept | GIR Grupo de Investigación en Acuicultura | - |
crisitem.author.dept | IU de Investigación en Acuicultura Sostenible y Ec | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.dept | GIR Grupo de Investigación en Acuicultura | - |
crisitem.author.dept | IU de Investigación en Acuicultura Sostenible y Ec | - |
crisitem.author.dept | GIR IUSA-ONE HEALTH 2 - Sanidad Animal de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas y Seguridad Alimentaria | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.dept | GIR IUSA-ONE HEALTH 2 - Sanidad Animal de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas y Seguridad Alimentaria | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.orcid | 0000-0001-6526-0354 | - |
crisitem.author.orcid | 0000-0002-1098-7529 | - |
crisitem.author.orcid | 0000-0002-3237-1020 | - |
crisitem.author.orcid | 0000-0003-0201-8338 | - |
crisitem.author.orcid | 0000-0002-6678-5029 | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.parentorg | IU de Investigación en Acuicultura Sostenible y Ec | - |
crisitem.author.parentorg | IU de Investigación en Acuicultura Sostenible y Ec | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.fullName | Real Valcárcel, Fernando | - |
crisitem.author.fullName | Acosta Arbelo, Félix Antonio | - |
crisitem.author.fullName | Bravo García,Jimena | - |
crisitem.author.fullName | Déniz Suárez, María Soraya | - |
crisitem.author.fullName | Padilla Castillo, Daniel Fermín | - |
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