|Title:||Simultaneous optimization of surfactant concentration and organic modifier in micellar liquid chromatography. Application to the separation of phenolic compounds||Authors:||Mahugo Santana,Cristina Isabel
Sosa Ferrera, Z.
Santana-Rodríguez, J. J.
|UNESCO Clasification:||2301 química analítica||Keywords:||Liquid chromatography
|Issue Date:||2000||Publisher:||0003-2719||Journal:||Analytical letters||Abstract:||The separation selectivity of eighteen phenolic derivatives in micellar high-performance liquid chromatography was studied as a function of parameters on which it depends: surfactant and organic modifier concentration. The surfactant used in this study was cetyltrimethylammonium bromide, and as organic modifier methanol. An iterative regression optimization strategy for these two parameters has been used. The equation that best explains the experimental results is 1/k' = A +Bμ + Cφ + DμΦ. We propose the use of this model in conjunction with the appropriate factorial design to predict the solute retention behaviour in micellar liquid chromatography with hibrid eluents.||URI:||http://hdl.handle.net/10553/47175||ISSN:||0003-2719||DOI:||10.1080/00032710008543154||Source:||Analytical Letters [ISSN 0003-2719], v. 33, p. 1691-1709|
|Appears in Collections:||Artículos|
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