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Title: New strategies of sample preparation in the analysis of pharmaceuticals and their determination using high performance liquid chromatography
Authors: Sosa-Ferrera, Zoraida 
Mahugo Santana,Cristina Isabel 
Esther Torres-Padrón, M. A. 
Santana-Rodríguez, José Juan 
UNESCO Clasification: 3209 Farmacología
23 Química
Keywords: Solid-Phase Microextraction
Bar Sorptive Extraction
Tandem Mass-Spectrometry
Microwave-Assisted Extraction
Molecularly Imprinted Polymers
Serotonin Reuptake Inhibitors
Trace-Level Determination
Sewage-Treatment Plants
Issue Date: 2010
Journal: Biomedical Chromatography 
Abstract: Pharmaceuticals are “emerging contaminants” in the environment, which have received increasing attention in recent years, in part, because these compounds are constantly being emitted into the environment in quantities similar to other organic contaminants, and thus may be candidates for future regulation. This paper reviews recently published data with respect to sample-preparation techniques for determining pharmaceutical traces in various different environmental matrices using liquid chromatography. An overview of multi-residue analytical methods, covering sample extraction and purification as well as chromatographic separation and various different detection methods is provided to illustrate common trends and method variability. Additionally, recent developments and advances in this field are presented
ISBN: 9781616684709
ISSN: 1099-0801
Source: Biomedical Chromatography [ISSN 1099-0801], p. 105-140
Appears in Collections:Capítulo de libro
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