Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47059
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dc.contributor.authorTriana Mendez,Jorgeen_US
dc.contributor.authorMarrero, María Teresaen_US
dc.contributor.authorBrouard, Ignacioen_US
dc.contributor.authorLeón, Franciscoen_US
dc.contributor.authorLopez Sanchez,Marianaen_US
dc.contributor.authorPerez Galvan,Francisco Javieren_US
dc.contributor.authorRico Santos, Milagrosen_US
dc.contributor.authorLópez-Monzón, Aroaen_US
dc.contributor.authorEstévez Rosas, Franciscoen_US
dc.contributor.otherBrouard, Ignacio-
dc.contributor.otherEstevez, Francisco-
dc.contributor.otherLeon, Francisco-
dc.contributor.otherRico, Milagros-
dc.date.accessioned2018-11-23T10:30:42Z-
dc.date.available2018-11-23T10:30:42Z-
dc.date.issued2012en_US
dc.identifier.issn1420-3049en_US
dc.identifier.urihttp://hdl.handle.net/10553/47059-
dc.description.abstractPhytochemical research of two Tolpis species, T. proustii and T. lagopoda, led to the isolation of three new compounds: 30-chloro-3beta-acetoxy-22alfa-hydroxyl-20(21)- taraxastene (1), 3beta,22alfa-diacetoxy-30-ethoxy-20(21)-taraxastene (2) and 3beta,28-dihydroxy- 11alfa-hydroperoxy-12-ursene (3). The structures of the new compounds were elucidated by means of extensive IR, NMR, and MS data and by comparison of data reported in the literature. The in vitro antioxidant activities of the extracts were assessed by the DPPH and ABTS scavenging methods. The cytotoxicity of several known compounds and its derivatives was also assessed against human myeloid leukemia K-562 and K-562/ADR cell lines.en_US
dc.formatapplication/pdf-
dc.languageengen_US
dc.relationAislamiento y Sistesis de Productos Naturales Con Actividad Citostitica de Plantas de la Familia Asteraceae Endemicas de Canarias.en_US
dc.relation.ispartofMoleculesen_US
dc.rightsby-nc-nd-
dc.sourceMolecules [ISSN 1420-3049], v. 17 (11), p. 12895-12909en_US
dc.subject230690 Química de productos naturales orgánicosen_US
dc.subject.otherAsteraceaeen_US
dc.subject.otherTolpis proustiien_US
dc.subject.otherTolpis lagopodaen_US
dc.subject.otherUrsane-triterpenesen_US
dc.subject.otherTaraxastane-triterpenesen_US
dc.titleSecondary metabolites from two species of tolpis and their biological activitiesen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/molecules171112895en_US
dc.identifier.scopus84870188272-
dc.identifier.isi000311428400032-
dcterms.isPartOfMolecules-
dcterms.sourceMolecules[ISSN 1420-3049],v. 17 (11), p. 12895-12909-
dc.contributor.authorscopusid55946071500-
dc.contributor.authorscopusid22985994700-
dc.contributor.authorscopusid57197103237-
dc.contributor.authorscopusid56228014200-
dc.contributor.authorscopusid37072953600-
dc.contributor.authorscopusid7003810011-
dc.contributor.authorscopusid55055343200-
dc.contributor.authorscopusid6603470039-
dc.contributor.authorscopusid7005039451-
dc.identifier.absysnet686089-
dc.description.lastpage12909en_US
dc.description.firstpage12895en_US
dc.relation.volume17en_US
dc.investigacionCienciasen_US
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess-
dc.type2Artículoen_US
dc.identifier.wosWOS:000311428400032-
dc.contributor.daisngid1400733-
dc.contributor.daisngid5158464-
dc.contributor.daisngid34494-
dc.contributor.daisngid2857141-
dc.contributor.daisngid4787857-
dc.contributor.daisngid384944-
dc.contributor.daisngid2743847-
dc.contributor.daisngid657275-
dc.contributor.daisngid136703-
dc.identifier.investigatorRIDK-5175-2014-
dc.identifier.investigatorRIDK-5125-2014-
dc.identifier.investigatorRIDNo ID-
dc.identifier.investigatorRIDNo ID-
dc.identifier.externalWOS:000311428400032-
dc.identifier.externalWOS:000311428400032-
dc.utils.revisionen_US
dc.date.coverdateNoviembre 2012en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-BASen_US
dc.description.sjr0,791
dc.description.jcr2,428
dc.description.sjrqQ1
dc.description.jcrqQ2
dc.description.scieSCIE
item.grantfulltextopen-
item.fulltextCon texto completo-
crisitem.author.deptGIR IOCAG: Química Marina-
crisitem.author.deptIU de Oceanografía y Cambio Global-
crisitem.author.deptDepartamento de Química-
crisitem.author.deptGIR Bioquímica Farmacológica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología.-
crisitem.author.deptGIR IOCAG: Química Marina-
crisitem.author.deptIU de Oceanografía y Cambio Global-
crisitem.author.deptDepartamento de Química-
crisitem.author.deptGIR Bioquímica Farmacológica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología.-
crisitem.author.orcid0000-0002-2711-8952-
crisitem.author.orcid0000-0002-9728-2774-
crisitem.author.orcid0000-0002-2711-8952-
crisitem.author.orcid0000-0002-9728-2774-
crisitem.author.parentorgIU de Oceanografía y Cambio Global-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Oceanografía y Cambio Global-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameTriana Mendez,Jorge-
crisitem.author.fullNameRico Santos, Milagros-
crisitem.author.fullNameLopez Sanchez,Mariana-
crisitem.author.fullNameEstévez Rosas, Francisco Jesús-
crisitem.author.fullNameRico Santos, Milagros-
crisitem.author.fullNameEstévez Rosas, Francisco Jesús-
crisitem.project.principalinvestigatorTriana Mendez,Jorge-
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