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Title: Biomarker responsiveness in different tissues of caged Ruditapes philippinarum and its use within an integrated sediment quality assessment
Authors: Ramos-Gómez, Julia
Coz, Alberto
Viguri, Javier R.
Luque, Ángel 
Martín-Díaz, M. Laura
DelValls, T. Ángel
UNESCO Clasification: 241705 Biología marina
Keywords: Bivalve
Exposure biomarkers
Effect biomarkers
Multivariate analysis
Integrated sediment quality
Issue Date: 2011
Publisher: 0269-7491
Journal: Environmental Pollution 
Abstract: Biomarkers comprising activities of biotransformation enzymes (ethoxyresorufin-O-deethylase –EROD–, dibenzylfluorescein dealkylase –DBF–, glutathione S-transferase –GST), antioxidant enzymes (glutathione reductase –GR– and glutathione peroxidase –GPX), lipid peroxidation –LPO– and DNA strand breaks were analyzed in the clam Ruditapes philippinarum caged at Cádiz Bay, Santander Bay and Las Palmas de Gran Canaria (LPGC) Port (Spain). Sediments were characterized. Digestive gland was the most sensitive tissue to sediment contamination. In Cádiz Bay, changes in LPO regarding day 0 were related with metals. In LPGC Port, DBF, EROD, and GST activity responses suggested the presence of undetermined contaminants which might have led to DNA damage. In Santander Bay, PAHs were related with EROD activity, organic and metal contamination was found to be associated with GR and GST activities and DNA damage presented significant (p < 0.05) induction. R. philippinarum was sensitive to sediment contamination at biochemical level. Biomarkers allowed chemical exposure and sediment quality assessment.
ISSN: 0269-7491
DOI: 10.1016/j.envpol.2011.03.030
Source: Environmental Pollution [ISSN 0269-7491], v. 159, p. 1914-1922
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