Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/46789
DC Field | Value | Language |
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dc.contributor.author | Sánchez-Hernández, Rosa M. | en_US |
dc.contributor.author | García-Cantón, César | en_US |
dc.contributor.author | Lorenzo, Dionisio L. | en_US |
dc.contributor.author | Quevedo, Virginia | en_US |
dc.contributor.author | Bosch, Elvira | en_US |
dc.contributor.author | López-Ríos, Laura | en_US |
dc.contributor.author | Riaño, Marta | en_US |
dc.contributor.author | Boronat, Mauro | en_US |
dc.date.accessioned | 2018-11-23T08:12:28Z | - |
dc.date.available | 2018-11-23T08:12:28Z | - |
dc.date.issued | 2015 | en_US |
dc.identifier.issn | 0301-0430 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/46789 | - |
dc.description.abstract | Aims: Vitamin D deficiency is highly prevalent in subjects with advanced chronic kidney disease (CKD), but diabetes, the most common cause of CKD, has also been linked to low levels of serum 25-hydroxyvitamin D [25(OH) D]. We compare vitamin D status between subjects with type 2 diabetes-related advanced CKD and subjects with either advanced CKD without diabetes or type 2 diabetes without advanced CKD. Methods: Subjects were patients with advanced CKD (estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m(2)) from February 2011 to November 2013 (113 with diabetes-related CKD and 80 without diabetes) and 61 patients with long-lasting type 2 diabetes without advanced CKD, simultaneously enrolled from our center. Participants fulfilled a survey questionnaire and underwent physical examination, blood samples, and 24-h urine collection. Kidney disease was assessed using eGFR and 24-h urinary protein excretion. Serum 25(OH) D was measured by chemiluminescence immunoassay. Results: The prevalence of vitamin D deficiency (25(OH) D < 20 ng/mL) was 70.8% in subjects with diabetes-related CKD, 38.8% in subjects with non-diabetic CKD and 41% in subjects with diabetes without advanced CKD. Adjusted means (95% confidence interval (CI)) of 25(OH) D in participants with diabetes-related CKD, in nondiabetic participants with CKD, and in participants with diabetes without advanced CKD were, respectively, 17.5 (14.2 - 20.7), 23.6 (19.4 - 27.8), and 23.5 (16.8 - 30.3) ng/mL (p = 0.023). Conclusions: Low vitamin D status is characteristically associated with advanced diabetic nephropathy. This relationship is not entirely attributable to the individual effects of CKD or long-lasting diabetes. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Clinical Nephrology | en_US |
dc.source | Clinical Nephrology[ISSN 0301-0430],v. 83, p. 218-224 | en_US |
dc.subject | 32 Ciencias médicas | en_US |
dc.subject | 320506 Nefrología | en_US |
dc.subject.other | 25-Hydroxyvitamin D Levels | en_US |
dc.subject.other | 3Rd National-Health | en_US |
dc.subject.other | Enhanced Excretion | en_US |
dc.subject.other | Association | en_US |
dc.subject.other | Megalin | en_US |
dc.title | The specific relationship between vitamin D deficiency and diabetic nephropathy among patients with advanced chronic kidney disease: A cross-sectional study in Gran Canaria, Spain | en_US |
dc.type | info:eu-repo/semantics/Article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.5414/CN108446 | en_US |
dc.identifier.scopus | 84933043064 | - |
dc.identifier.isi | 000352238000003 | - |
dc.contributor.authorscopusid | 57203232814 | - |
dc.contributor.authorscopusid | 6603127359 | - |
dc.contributor.authorscopusid | 55967938300 | - |
dc.contributor.authorscopusid | 57188624099 | - |
dc.contributor.authorscopusid | 36027905600 | - |
dc.contributor.authorscopusid | 33068166900 | - |
dc.contributor.authorscopusid | 37067926100 | - |
dc.contributor.authorscopusid | 7003952293 | - |
dc.description.lastpage | 224 | en_US |
dc.description.firstpage | 218 | en_US |
dc.relation.volume | 83 | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.contributor.daisngid | 3858758 | - |
dc.contributor.daisngid | 1915819 | - |
dc.contributor.daisngid | 30519221 | - |
dc.contributor.daisngid | 5112593 | - |
dc.contributor.daisngid | 1780664 | - |
dc.contributor.daisngid | 1964185 | - |
dc.contributor.daisngid | 5257474 | - |
dc.contributor.daisngid | 673494 | - |
dc.description.numberofpages | 7 | en_US |
dc.utils.revision | Sí | en_US |
dc.contributor.wosstandard | WOS:Sanchez-Hernandez, RM | - |
dc.contributor.wosstandard | WOS:Garcia-Canton, C | - |
dc.contributor.wosstandard | WOS:Lorenzo, DL | - |
dc.contributor.wosstandard | WOS:Quevedo, V | - |
dc.contributor.wosstandard | WOS:Bosch, E | - |
dc.contributor.wosstandard | WOS:Lopez-Rios, L | - |
dc.contributor.wosstandard | WOS:Riano, M | - |
dc.contributor.wosstandard | WOS:Boronat, M | - |
dc.date.coverdate | Abril 2015 | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-MED | en_US |
dc.description.sjr | 0,519 | |
dc.description.jcr | 1,065 | |
dc.description.sjrq | Q3 | |
dc.description.jcrq | Q4 | |
dc.description.scie | SCIE | |
item.fulltext | Sin texto completo | - |
item.grantfulltext | none | - |
crisitem.author.dept | Departamento de Ciencias Médicas y Quirúrgicas | - |
crisitem.author.dept | GIR IUIBS: Diabetes y endocrinología aplicada | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Ciencias Médicas y Quirúrgicas | - |
crisitem.author.orcid | 0000-0002-5988-8222 | - |
crisitem.author.orcid | 0000-0001-8535-8543 | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.fullName | García Cantón, César | - |
crisitem.author.fullName | Lorenzo Villegas, Dionisio Lorenzo | - |
crisitem.author.fullName | Boronat Cortés, Mauro | - |
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