Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/46698
Title: Reliability of the bronchoscopic protected catheter brush in the diagnosis of pneumonia in mechanically ventilated patients
Authors: Rodriguez de Castro, F. 
Sole Violan, Jorge 
Capuz, B. L.
Luna, J. C. 
Rodriguez, B. G.
Alonso, J. L.M.
UNESCO Clasification: 32 Ciencias médicas
3205 Medicina interna
3213 Cirugía
Keywords: Bronchoscopy
Catheter brush
Pneumonia
Mechanically ventilated patients
Issue Date: 1991
Journal: Critical Care Medicine 
Abstract: Objective: To assess the usefulness of the telescoping plugged catheter in the diagnosis of nosocomial pneumonia. Design: Prospective study. Patients: A total of 103 ventilated patients with suspected pneumonia were prospectively studied over 20 months. Results: The quantitative cultures of the protected brush specimen detected pulmonary bacterial infection (greater than 10(3) cfu/mL) in 49 (47.5%) patients. Subsequent follow-up confirmed pneumonia in 41 patients; in only one patient was a positive protected brush specimen culture established as a false-positive result. There were 54 patients with less than 10(3) cfu/mL and the diagnosis was excluded in 36 of them. We identified eight patients with false-negative protected brush specimen cultures. The results obtained by this technique allowed us to modify treatment in 49 (47.5%) patients. Conclusions: The telescoping plugged catheter demonstrated significant bacterial infection in a relatively small proportion of patients in whom bacterial lung infection was suspected. This technique can be safely performed and is a sensitive and specific method to establish the cause of pneumonia, thus allowing specific treatment and the avoidance of inappropriate antibiotic therapy.
URI: http://hdl.handle.net/10553/46698
ISSN: 0090-3493
DOI: 10.1097/00003246-199102000-00010
Source: Critical Care Medicine[ISSN 0090-3493],v. 19, p. 171-175
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