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Title: Comparison of bronchoscopic diagnostic techniques with histological findings in brain dead organ donors without suspected pneumonia
Authors: Sole Violan, Jorge 
De Castro, Felipe Rodríguez 
Rey, Agustín
Freixinet, Jorge 
Aranda, Agustín
Caminero, José
Bolaños, José
UNESCO Clasification: 32 Ciencias médicas
3201 Ciencias clínicas
Keywords: Ventilator-Associated Pneumonia
Critically Ill
Bronchoscopic diagnostic techniques
Issue Date: 1996
Journal: Thorax 
Abstract: Background - The techniques for recognising pneumonia in mechanically ventilated patients were evaluated as no ''gold standard'' is available to establish the diagnosis in these patients.Methods - A prospective study was performed on nine brain dead organ donors not suspected of having pneumonia to assess the specificity of bacteriological results from different samples by comparing them with the histological findings from an open pulmonary biopsy specimen taken immediately after death through a mini-thoracotomy.Results - Seven of the nine organ donors without clinical evidence of pulmonary infection and not on antibiotic therapy showed histological features of bronchopneumonia. There was no association between the histological findings and quantitative cultures of the lung biopsy specimen.Conclusions - Histological evidence of pneumonia was common in this group of ventilated patients who had no clinical signs of the disease.
ISSN: 0040-6376
DOI: 10.1136/thx.51.9.929
Source: Thorax[ISSN 0040-6376],v. 51, p. 929-931
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