Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/45926
Title: Effectiveness of the physical activity intervention program in the PREDIMED-Plus study: a randomized controlled trial
Authors: Schröder, Helmut
Cárdenas-Fuentes, Gabriela
Martínez-González, Miguel Angel
Corella, Dolores
Vioque, Jesús
Romaguera, Dora
Alfredo Martínez, J.
Tinahones, Francisco J.
Miranda, José López
Estruch, Ramon
Bueno-Cavanillas, Aurora
Arós, Fernando
Marcos, Ascensión
Tur, Josep A.
Warnberg, Julia
Serra-Majem, Lluis 
Martín, Vicente
Vázquez, Clotilde
Lapetra, José
Pintó, Xavier
Vidal, Josep
Daimiel, Lidia
Gaforio, José Juan
Matía-Martín, Pilar
Ros, Emilio
Castañer, Olga
Lassale, Camille
Ruiz-Canela, Miguel
Asensio, Eva M.
Basora, Josep
Torres-Collado, Laura
Garcia-Rios, Antonio
Abete, Itziar
Toledo, Estefania
Buil-Cosiales, Pilar
Bullo, Mònica
Goday, Albert
Fitó, Montserrat
Salas-Salvadó, Jordi
UNESCO Clasification: 32 Ciencias médicas
Keywords: Older-Adults
Cardiovascular-Disease
Prevention
Behavior
Randomized Control Trial, et al
Issue Date: 2018
Journal: International Journal of Behavioral Nutrition and Physical Activity 
Abstract: Background: The development and implementation of effective physical activity (PA) intervention programs is challenging, particularly in older adults. After the first year of the intervention program used in the ongoing PREvención con DIeta MEDiterránea (PREDIMED)-Plus trial, we assessed the initial effectiveness of the PA component. Methods: PREDIMED-Plus is an ongoing randomized clinical trial including 6874 participants randomized to an intensive weight-loss lifestyle intervention based on an energy-restricted Mediterranean diet (MedDiet), physical activity promotion and behavioral support and to a control group using MedDiet recommendations but without calorie restriction or PA advice. Body mass index (BMI) and waist circumference (WC) are measured by standard clinical protocols. Duration and intensity of PA is self-reported using the validated REGICOR Short Physical Activity Questionnaire. The primary endpoint of the PREDIMED-Plus trial is a combined cardiovascular outcome: myocardial infarction (acute coronary syndromes with positive troponin test), stroke, or cardiovascular mortality. The present study involved secondary analysis of PA data (n = 6059; mean age 65 ± 4.9 years) with one-year changes in total, light, and moderate-to-vigorous PA within and between intervention groups as the outcome. Generalized estimating equation models were fitted to evaluate time trends of PA, BMI, and WC within groups and differences between intervention and control groups Results: After 12 months, average daily MVPA increased by 27.2 (95%CI 5.7;48.7) METs-min/day and 123.1 (95%CI 109. 7–136.6) METs-min/day in the control and intervention groups, respectively. Total-PA, light-PA, and MVPA increased significantly (p < 0.01) in both groups. A significant (p < 0.001) time*intervention group interaction was found for Total-PA and MVPA, meaning the PA trajectory over time differed between the intervention and control groups. Age, sex, education level, and BMI did not moderate the effectiveness of the PA intervention. BMI and WC decreased significantly with increasing MVPA, compared with participants who reported no changes in MVPA.
URI: http://hdl.handle.net/10553/45926
ISSN: 1479-5868
DOI: 10.1186/s12966-018-0741-x
Source: International Journal Of Behavioral Nutrition And Physical Activity [ISSN 1479-5868], v. 15, (Noviembre 2018)
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