Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/45861
Title: Non-specific reactive hepatitis in dolphins stranded in the Canary Islands
Authors: Jaber, José Raduan 
Pérez, Jose
Carrascosa, Conrado 
Carballo, Matilde
Fernández, Antonio 
Keywords: Polychlorinated-Biphenyls
Tursiops-Truncatus
Organohalogen Contaminants
Phocoena-Phocoena
Harbor Porpoises, et al
Issue Date: 2013
Publisher: 0971-2119
Journal: Journal of Applied Animal Research 
Abstract: This paper describes the features of non-specific reactive hepatitis (NSRH) in dolphins stranded on the coast of the Canary Islands (Spain). The histological appearance of NSRH was marked by the proliferation of Kupffer cells and the presence of granulocytes, plus lymphocytes and plasma cells scattered throughout the liver parenchyma and in the portal or perivenular stroma, without or with minimal evidence of hepatocyte necrosis. NSRH was composed of inflammatory infiltration of CD3(+) T-lymphocytes and IgG(+) plasma cells in the portal spaces and hepatic sinusoids. The anti-S100 protein polyclonal antibody reacted with a variable number of lymphocytes from the portal areas and hepatic sinusoids and with Kupffer cells and the epithelial cells of the bile ducts.
URI: http://hdl.handle.net/10553/45861
ISSN: 0971-2119
DOI: 10.1080/09712119.2013.787363
Source: Journal of Applied Animal Research[ISSN 0971-2119],v. 41, p. 398-403
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