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http://hdl.handle.net/10553/45834
Title: | Long-term efficacy of trilostane administered twice daily in dogs with pituitary-dependent hyperadrenocorticism | Authors: | Pérez Alenza, Dolores Arenas, Carolina Lopez, Mari Luz Melián Limiñana, Carlos |
UNESCO Clasification: | 310907 Patología | Keywords: | Trilostane Hyperadrenocorticism Dogs |
Issue Date: | 2006 | Publisher: | 1547-3317 | Journal: | Journal of the American Animal Hospital Association | Abstract: | Trilostane is considered an efficacious and safe medication for canine pituitary-dependent hyperadrenocorticism (PDH). Its recommended frequency of administration is once daily. In this prospective study, the efficacy, toxicity, and long-term outcome of trilostane administered twice daily per os were evaluated in 44 dogs with PDH. Mean initial dose was 3.1 mg/kg q 12 hours, and mean final dose was 3.2 mg/kg q 12 hours. The final total daily dose was lower than previously reported for once-daily administration. The mean survival time for affected dogs was 930 days. | URI: | http://hdl.handle.net/10553/45834 | ISSN: | 1547-3317 | DOI: | 10.5326/0420269 | Source: | Journal of the American Animal Hospital Association [ISSN 1547-3317], v. 42, p. 269-276 |
Appears in Collections: | Artículos |
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