Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/45352
Título: SDS-PAGE analysis of urinary proteins in dogs with heartworm disease
Autores/as: Beristain-Ruiz, D. M.
Carretón Gomez, Elena 
Rodríguez-Alarcón, C. A.
Montoya Alonso, José Alberto 
Barrera, R.
Clasificación UNESCO: 240112 Parasitología animal
310907 Patología
Palabras clave: Dirofilaria immitis
SDS-PAGE
Proteinuria
Fecha de publicación: 2013
Editor/a: 1728-1997
Publicación seriada: Iranian Journal of Veterinary Research 
Resumen: The aim of the study was to describe the urinary electrophoretic pattern of dogs with heartworm disease. Urine samples from 15 heartworm-infected and 15 healthy dogs were taken. Urinary specific gravity, urinary protein concentration and the urine protein/creatinine (U P/C) ratio were determined. Urine proteins were fractionated using SDS-PAGE. Results showed statistically significant differences for the U P/C ratio (P<0.05) but not for USG and urinary protein concentrations (P>0.05) between groups. Urinary protein SDSPAGE analysis showed eight distinct bands in the urine of heartworm-infected dogs. The presence of proteins exclusively found in the urine of infected dogs suggests renal damage, even in cases of light proteinuria, indicating that SDS-PAGE is a sensitive method for the identification and characterisation of renal proteinuria in dogs with heartworm disease.
URI: http://hdl.handle.net/10553/45352
ISSN: 1728-1997
Fuente: Iranian Journal of Veterinary Research [ISSN 1728-1997], v. 14, p. 245-249
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