Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/45348
Title: Effects of low-fat high-fibre diet and mitratapide on body weight reduction, Blood pressure and metabolic parameters in obese dogs
Authors: Peña, Cristina
Suarez, Lourdes
Bautista Castaño, Inmaculada 
Juste de Santa Ana, Candelaria 
Carretón Gomez, Elena 
Montoya Alonso, José Alberto 
UNESCO Clasification: 310907 Patología
310906 Nutrición
Keywords: Canine
Hiperlipidaemia
Hypertension
Mitratapide
Obesity
Issue Date: 2014
Publisher: 0916-7250
Journal: Journal of Veterinary Medical Science 
Abstract: The aim of the present study was to compare the impact on blood pressure and different metabolic parameters of a weight-loss program on obese dogs fed on a low-fat high-fibre diet and treated with and without mitratapide. The study sample consisted of 36 obese dogs, randomly assigned to a control group (n=17), which were fed on a low-fat high-fibre diet, and an intervention group (n=19), fed on the same diet and treated with mitratapide. Variables measured included body condition score, body weight, heart rate, systolic and diastolic blood pressures; total cholesterol, triglycerides and glucose levels; alanine aminotransferase and alkaline phosphatase activity, measured both at baseline (day 0) and at the end of the weight loss program (day 85). All the studied parameters had decreased in both groups at the end of the study; these being diastolic blood pressure, total cholesterol and alanine aminotransferase, significantly lower in dogs treated with mitratapide. The use of mitrapide in addition to low-fat high-fibre diet does not seem to offer any further useful effect in the loss of weight during the treatment of canine obesity. On the other hand, mitratapide seems to present certain beneficial effects on pathologies associated with obesity, these being mainly related to blood pressure, lipids and hepatic parameters.
URI: http://hdl.handle.net/10553/45348
ISSN: 0916-7250
DOI: 10.1292/jvms.13-0475
Source: Journal of Veterinary Medical Science [ISSN 0916-7250], v. 76, p. 1305-1308
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