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Title: Predictor of the grade of handicap in patients with multiple sclerosis
Authors: Déniz Cáceres, A. 
Saavedra, P.
Marrero, I. 
UNESCO Clasification: 32 Ciencias médicas
3212 Salud pública
Keywords: Multiple sclerosis
Issue Date: 2011
Journal: Rehabilitacion 
Abstract: Introduction and objectives: Multiple sclerosis (MS) is most frequent and disabling chronic neurological disease in young adults. This study has aimed to, based on the relation between EDSS (Expanded Disability Status Scale of Kurtzke) and the grade of handicap of MS patients, obtain a predictor of the handicap grade that would allow the clinicians to orient the patient on the social aid program and tax benefits that they are entitled to. Material and methods: A cross-sectional study was performed on 67 MS-diagnosed patients who had been previously assigned a EDSS grade of disability during their respective neurological evaluations. After, we evaluated the individual handicap grade in these patients, using the scale for the «The Grade of handicap» (RD 1971/1999, of 23 december). The statistical study of the data was performed using the last generation statistical program of R Development Core Team (R). Results: The graphical representation of the EDSS and the respective handicap grades allowed us to develop a statistical model of simple linear regression, which is as follows:P.Mi=α+β(EDSS)+ei P.Mi = handicap degree (EDSS value dependent) α = -14.23 β = 12.49 ei = biological variability Using this model, we calculated the percentages of handicap for each value of the EDSS with a 95% confidence interval. Conclusions: The statistical model allows us to use the Kurtzke Expanded Disability Status Scale as a predictor of the handicap grade of MS patients.
ISSN: 0048-7120
DOI: 10.1016/j.rh.2011.08.003
Source: Rehabilitacion [ISSN 0048-7120], v. 45, p. 301-307
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