Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/44947
Título: Vegetable lipid sources affect in vitro biosynthesis of triacylglycerols and phospholipids in the intestine of sea bream (Sparus aurata)
Autores/as: Caballero Cansino, María José 
Gallardo Campos, Germán 
Robaina Robaina, Lidia Esther 
Montero Vítores, Daniel 
Fernández Rodríguez, Antonio Jesús 
Izquierdo López, María Soledad 
Clasificación UNESCO: 251092 Acuicultura marina
230218 Lípidos
310406 Nutrición
Palabras clave: Intestinal microsomes
Vegetable oils
Sea bream
Monoacylglycerol pathways
Cytidine diphosphate nucleotides, et al.
Fecha de publicación: 2006
Publicación seriada: British Journal of Nutrition 
Resumen: Despite the good growth performance of several fish species when dietary fish oil is partly replaced by vegetable oils, recent studies have reported several types of intestinal morphological alterations in cultured fish fed high contents of vegetable lipid sources. However, the physiological process implied in these morphological changes have not been clarified yet, since alterations in the physiological mechanisms involved in the different processes of lipid absorption could be responsible for such gut morphological features. The objective of the present study was to investigate the activities of reacylation pathways in fish, the glycerol-3-phosphate and the monoacylglycerol pathways, in order to clarify the intestinal triacylglycerol (TAG) and phospholipid biosynthesis to better understand the morphological alterations observed in the intestine of fish fed vegetable oils. Intestinal microsomes of sea bream fed different lipid sources (fish, soyabean and rapeseed oils) at three different inclusion levels were isolated and incubated with l-[14C(U)]glycerol-3-phosphate and [1-14C]palmitoyl CoA. The results showed that in this fish species the glycerol-3-phosphate pathway is mainly involved in phospholipid synthesis, whereas TAG synthesis is mainly mediated by the monoacylglycerol pathway. Feeding with rapeseed oil reduced the reacylation activity in both pathways, explaining the high accumulation of lipid droplets in the supranuclear portion of the intestinal epithelium, whereas soyabean oil enhanced phosphatidylcholine synthesis, being associated with the increase in VLDL found in previous studies.
URI: http://hdl.handle.net/10553/44947
ISSN: 0007-1145
DOI: 10.1079/BJN20051529
Fuente: British Journal of Nutrition [ISSN 0007-1145], v. 95, p. 448-454
Colección:Artículos
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