Association of Tryptophan Metabolites with Incident Type 2 Diabetes in the PREDIMED Trial: A Case-Cohort Study

Title:	Association of Tryptophan Metabolites with Incident Type 2 Diabetes in the PREDIMED Trial: A Case-Cohort Study
Authors:	Yu, Edward Papandreou, Christopher Ruiz-Canela, Miguel Guasch-Ferre, Marta Clish, Clary B. Dennis, Courtney Liang, Liming Corella, Dolores Fitó, Montserrat Razquin, Cristina Lapetra, José Estruch, Ramón Ros, Emilio Cofán, Montserrat Arós, Fernando Toledo, Estefania Serra-Majem, Lluis Sorlí, José V. Hu, Frank B. Martinez-Gonzalez, Miguel A. Salas-Salvado, Jordi
UNESCO Clasification:	2403 Bioquímica 2301 química analítica
Keywords:	Diabetes Insulin Metabolites Risk analysis Cardiovascular disease
Issue Date:	2018
Publisher:	0009-9147
Journal:	Clinical chemistry (Baltimore, Md.)
Abstract:	BACKGROUND: Metabolites of the tryptophan-kynurenine pathway (i.e., tryptophan, kynurenine, kynurenic acid, quinolinic acid, 3-hydroxyanthranilic) may be associated with diabetes development. Using a case-cohort design nested in the Prevencion con Dieta Mediterranea (PREDIMED) study, we studied the associations of baseline and 1-year changes of these metabolites with incident type 2 diabetes (T2D).
URI:	http://hdl.handle.net/10553/44599
ISSN:	0009-9147
DOI:	10.1373/clinchem.2018.288720
Source:	Clinical Chemistry [ISSN 0009-9147], v. 64 (8), p. 1211-1220
Appears in Collections:	Artículos

Show full item record