Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/44484
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Olmedillas, Hugo | en_US |
dc.contributor.author | Sanchis-Moysi, Joaquin | en_US |
dc.contributor.author | Fuentes, Teresa | en_US |
dc.contributor.author | Guadalupe, Amelia | en_US |
dc.contributor.author | Ponce-González, Jesús G. | en_US |
dc.contributor.author | Morales Alamo, David | en_US |
dc.contributor.author | Santana Rodríguez, Alfredo | en_US |
dc.contributor.author | Dorado, Cecilia | en_US |
dc.contributor.author | Calbet, Jose A. L. | en_US |
dc.contributor.author | Guerra, Borja | en_US |
dc.contributor.other | Guerra, Borja | - |
dc.contributor.other | Ponce Gonzalez, Jesus Gustavo | - |
dc.contributor.other | Fuentes, Teresa | - |
dc.contributor.other | Morales-Alamo, David | - |
dc.contributor.other | Guadalupe-Grau, Amelia | - |
dc.contributor.other | Cecilia, Dorado-Garcia | - |
dc.contributor.other | SANCHIS-MOYSI, JOAQUIN | - |
dc.contributor.other | Calbet, Jose A | - |
dc.contributor.other | Olmedillas, Hugo | - |
dc.date.accessioned | 2018-11-21T23:57:34Z | - |
dc.date.available | 2018-11-21T23:57:34Z | - |
dc.date.issued | 2010 | en_US |
dc.identifier.issn | 1439-6319 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/44484 | - |
dc.description.abstract | In rodents, endurance training increases leptin sensitivity in skeletal muscle; however, little is known about the effects of exercise on the leptin signalling system in human skeletal muscle. Thus, to determine whether chronic muscle loading increases leptin receptor (OB-R170) protein expression, body composition dual-energy X-ray absorptiometry was assessed in nine professional male tennis players (24 ± 4 years old) and muscle biopsies were obtained from the dominant (DTB) and non-dominant (NDTB) arm triceps brachii (TB), and also from the right vastus lateralis (VL). In each biopsy, the protein content of OB-R170, perilipin A, suppressor of cytokine signalling 3 (SOCS3), protein tyrosine phosphatase 1B (PTP1B) and signal transducer and activator of transcription 3 (STAT3) phosphorylation were determined by western blot. The DTB had 15% greater lean mass (P < 0.05) and 62% greater OB-R170 protein expression (P < 0.05) than the NDTB. SOCS3 and PTP1B protein expression was similar in both arms, while STAT3 phosphorylation was reduced in the NDTB. OB-R170 protein content was also higher in DTB than in VL (P < 0.05). In summary, this study shows that the functional isoform of the leptin receptor is up-regulated in the hypertrophied TB. The latter combined with the fact that both SOCS3 and PTP1B protein expression were unaltered is compatible with increased leptin sensitivity in this muscle. Our findings are also consistent with a role of leptin signalling in muscle hypertrophy in healthy humans. | en_US |
dc.language | eng | en_US |
dc.publisher | 1439-6319 | - |
dc.relation.ispartof | European Journal of Applied Physiology | en_US |
dc.source | European Journal Of Applied Physiology[ISSN 1439-6319],v. 108 (4), p. 749-758 | en_US |
dc.subject | 241106 Fisiología del ejercicio | en_US |
dc.subject.other | Hypertrophy, Leptin, PTP1B, SOCS3, STAT3, Tennis | en_US |
dc.title | Muscle hypertrophy and increased expression of leptin receptors in the musculus triceps brachii of the dominant arm in professional tennis players | en_US |
dc.type | info:eu-repo/semantics/Article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1007/s00421-009-1281-5 | en_US |
dc.identifier.scopus | 77950865754 | - |
dc.identifier.isi | 000274495500015 | - |
dcterms.isPartOf | European Journal Of Applied Physiology | - |
dcterms.source | European Journal Of Applied Physiology[ISSN 1439-6319],v. 108 (4), p. 749-758 | - |
dc.contributor.authorscopusid | 23051517000 | - |
dc.contributor.authorscopusid | 6507016623 | - |
dc.contributor.authorscopusid | 16301115800 | - |
dc.contributor.authorscopusid | 25627673000 | - |
dc.contributor.authorscopusid | 25628359100 | - |
dc.contributor.authorscopusid | 35148038500 | - |
dc.contributor.authorscopusid | 55617275900 | - |
dc.contributor.authorscopusid | 6602610320 | - |
dc.contributor.authorscopusid | 7004323423 | - |
dc.contributor.authorscopusid | 7006442271 | - |
dc.description.lastpage | 758 | en_US |
dc.description.firstpage | 749 | en_US |
dc.relation.volume | 108 | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.identifier.wos | WOS:000274495500015 | - |
dc.contributor.daisngid | 954582 | - |
dc.contributor.daisngid | 1763347 | - |
dc.contributor.daisngid | 1500209 | - |
dc.contributor.daisngid | 861361 | - |
dc.contributor.daisngid | 7526316 | - |
dc.contributor.daisngid | 1264657 | - |
dc.contributor.daisngid | 1232764 | - |
dc.contributor.daisngid | 31470516 | - |
dc.contributor.daisngid | 1230811 | - |
dc.contributor.daisngid | 629383 | - |
dc.contributor.daisngid | 90295 | - |
dc.contributor.daisngid | 909211 | - |
dc.identifier.investigatorRID | G-9739-2015 | - |
dc.identifier.investigatorRID | H-9500-2015 | - |
dc.identifier.investigatorRID | K-7227-2014 | - |
dc.identifier.investigatorRID | D-2683-2009 | - |
dc.identifier.investigatorRID | H-4961-2016 | - |
dc.identifier.investigatorRID | B-4586-2010 | - |
dc.identifier.investigatorRID | H-7017-2015 | - |
dc.identifier.investigatorRID | H-6693-2015 | - |
dc.identifier.investigatorRID | No ID | - |
dc.contributor.wosstandard | WOS:Olmedillas, H | - |
dc.contributor.wosstandard | WOS:Sanchis-Moysi, J | - |
dc.contributor.wosstandard | WOS:Fuentes, T | - |
dc.contributor.wosstandard | WOS:Guadalupe-Grau, A | - |
dc.contributor.wosstandard | WOS:Ponce-Gonzalez, JG | - |
dc.contributor.wosstandard | WOS:Morales-Alamo, D | - |
dc.contributor.wosstandard | WOS:Santana, A | - |
dc.contributor.wosstandard | WOS:Dorado, C | - |
dc.contributor.wosstandard | WOS:Calbet, JAL | - |
dc.contributor.wosstandard | WOS:Guerra, B | - |
dc.date.coverdate | Marzo 2010 | en_US |
dc.identifier.ulpgc | Sí | es |
dc.description.jcr | 2,214 | |
dc.description.jcrq | Q2 | |
dc.description.scie | SCIE | |
item.fulltext | Sin texto completo | - |
item.grantfulltext | none | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Educación Física | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Educación Física | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Ciencias Clínicas | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Educación Física | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Educación Física | - |
crisitem.author.dept | GIR IUIBS: Farmacología Molecular y Traslacional | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Ciencias Clínicas | - |
crisitem.author.orcid | 0000-0001-6602-7087 | - |
crisitem.author.orcid | 0000-0003-1286-8731 | - |
crisitem.author.orcid | 0000-0001-8463-397X | - |
crisitem.author.orcid | 000-0002-1075-9948 | - |
crisitem.author.orcid | 0000-0001-6616-6810 | - |
crisitem.author.orcid | 0000-0002-9215-6234 | - |
crisitem.author.orcid | 0000-0003-4355-5682 | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.fullName | Sanchís Moysi, Joaquín | - |
crisitem.author.fullName | Hernández Delgado, Teresa De Jesús | - |
crisitem.author.fullName | Guadalupe Grau,Amelia | - |
crisitem.author.fullName | Morales Álamo, David | - |
crisitem.author.fullName | Santana Rodríguez, Alfredo | - |
crisitem.author.fullName | Dorado García, Cecilia | - |
crisitem.author.fullName | López Calbet, José Antonio | - |
crisitem.author.fullName | Guerra Hernández, Carlos Borja | - |
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