Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/43730
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dc.contributor.authorMartínez-Quintana, Efrénen_US
dc.contributor.authorRodríguez-González, Faynaen_US
dc.contributor.authorFábregas-Brouard, Marianen_US
dc.contributor.authorNieto-Lago, Vicenteen_US
dc.date.accessioned2018-11-21T17:23:43Z-
dc.date.available2018-11-21T17:23:43Z-
dc.date.issued2009en_US
dc.identifier.issn1747-079Xen_US
dc.identifier.urihttp://hdl.handle.net/10553/43730-
dc.description.abstractIntroduction. Glomerulopathy is a complication of congenital heart disease patients. The risk of developing renal impairment is particularly high in cyanotic patients. Objective. The aim of this study was to determine the prevalence of renal dysfunction and microalbumiuria in adult cyanotic and non cyanotic congenital heart disease patients. Methods. Fourteen cyanotic and 22 noncyanotic congenital heart disease patients were studied in the Adult Congenital Heart Disease Unit at the Complejo Hospitalario Universitario Insular‐Materno Infantil. Demographic characteristics, complete blood count, and 24‐hour urianalysis were obtained, including abdominal ultrasound in those with cyanosis. Results. No differences were seen between age (years) (27.4 ± 8.2; 26.4 ± 8.3; P = .71), sex, size, weight, or glomerular filtration rate (mL/min/1.73 m2) (81.1 ± 22.9 vs. 84.9 ± 9.2, P = .482) between cyanotic and noncyanotic patients. However, Eisenmenger patients had significantly impaired renal function when compared with noncyanotic patients (73.0 ± 17.3 vs. 84.9 ± 9.2 mL/min/1.73 m2, P = .023). Significant differences were obtained in oxygen saturation (%) (83.8 ± 5.8 vs. 97.8 ± 0.8; P = .000), hematocrit (%) (59.3 ± 8.1 vs. 40.9 ± 8.5; P = .000), platelets (103/µL) (161.5 ± 70.5 vs. 277.9 ± 57.6; P = .000), serum uric acid (mg/dL) (7.5 ± 2.3 vs. 5.6 ± 1.5; P = .008) and microalbuminuria (mg/24 hours) (12.8 [0, 700.2] vs. 2.4 [0, 18.9]; P = .000) between cyanotic and noncyanotic patients. Five cyanotic patients (35.7%) had microalbuminuria (>30 mg/24 hours) and three of them (21.4%) proteinuria (>1 g/24 hours). No significant differences were seen between serum and urine parameters between cyanotic patients who had microalbuminuria (>30 mg/24 hours) and those cyanotic patients who did not have it (<30 mg/24 hours). Conclusions. Renal impairment is frequently seen in congenital heart disease patients, being associated occasionally with proteinuria and microalbuminuria in cyanotic ones.en_US
dc.languageengen_US
dc.publisher1747-079X-
dc.relation.ispartofCongenital Heart Diseaseen_US
dc.sourceCongenital Heart Disease [ISSN 1747-079X], v. 4, p. 147-152en_US
dc.subject320501 Cardiologíaen_US
dc.subject.otherProteinuriaen_US
dc.subject.otherMicroalbuminuriaen_US
dc.subject.otherImpaired renal functionen_US
dc.subject.otherCyanoticen_US
dc.subject.otherCongenital heart diseaseen_US
dc.titleSerum and 24-hour urine analysis in adult cyanotic and noncyanotic congenital heart disease patientsen_US
dc.typeinfo:eu-repo/semantics/articlees
dc.typeArticlees
dc.identifier.doi10.1111/j.1747-0803.2009.00273.xen_US
dc.identifier.scopus66649098693-
dc.contributor.authorscopusid23485891800-
dc.contributor.authorscopusid24825586600-
dc.contributor.authorscopusid57194412026-
dc.contributor.authorscopusid8642874100-
dc.description.lastpage152-
dc.description.firstpage147-
dc.relation.volume4-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.ulpgces
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.fullNameMartínez Quintana, Efrén-
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