Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10553/43681
Campo DC | Valor | idioma |
---|---|---|
dc.contributor.author | Martínez Quintana, Efrén | en_US |
dc.contributor.author | Rodríguez-González, Fayna | en_US |
dc.date.accessioned | 2018-11-21T17:02:15Z | - |
dc.date.available | 2018-11-21T17:02:15Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.issn | 1047-9511 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/43681 | - |
dc.description.abstract | Subclinical hypothyroidism or mild thyroid failure is a common problem in patients without known thyroid disease. Methods: Demographic and analytical data were collected in 309, of which 181 were male and 128 were female, congenital heart disease (CHD) patients. CHD patients with thyroid-stimulating hormone above 5.5 mIU/L were also followed up from an analytical point of view to determine changes in serum glucose, cholesterol, N-terminal pro b-type natriuretic peptide, and C-reactive protein concentrations. Results: Of the CHD patients, 35 (11.3%) showed thyroid-stimulating hormone concentration above 5.5 mIU/L. Of them, 27 were followed up during 2.4±1.2 years – 10 were under thyroid hormone replacement treatment, and 17 were not. Of the 27 patients (25.9%), 7 with subclinical hypothyroidism had positive anti-thyroid peroxidase, and 3 of them (42.8%) with positive anti-thyroid peroxidase had Down syndrome. Down syndrome and hypoxaemic CHD patients showed higher thyroid-stimulating hormone concentrations than the rest of the congenital patients (p<0.001). No significant differences were observed in serum thyroxine, creatinine, uric acid, lipids, C-reactive protein, or N-terminal pro b-type natriuretic peptide concentrations before and after the follow-up in those CHD patients with thyroid-stimulating hormone above 5.5 mIU/L whether or not they received levothyroxine therapy. Conclusions: CHD patients with subclinical hypothyroidism showed no significant changes in serum thyroxine, cholesterol, C-reactive protein, or N-terminal pro b-type natriuretic peptide concentrations whether or not they were treated with thyroid hormone replacement therapy. | en_US |
dc.language | eng | en_US |
dc.publisher | 1047-9511 | - |
dc.relation.ispartof | Cardiology in the Young | en_US |
dc.source | Cardiology in the Young [ISSN 1047-9511], v. 25, p. 1111-1118 | en_US |
dc.subject | 320501 Cardiología | en_US |
dc.subject.other | Subclinical hypothyroidism | en_US |
dc.subject.other | Follow-up | en_US |
dc.subject.other | CHD | en_US |
dc.title | Follow-up of congenital heart disease patients with subclinical hypothyroidism | en_US |
dc.type | info:eu-repo/semantics/article | es |
dc.type | Article | es |
dc.identifier.doi | 10.1017/S1047951114001711 | en_US |
dc.identifier.scopus | 84945464389 | - |
dc.contributor.authorscopusid | 23485891800 | - |
dc.contributor.authorscopusid | 24825586600 | - |
dc.description.lastpage | 1118 | - |
dc.description.firstpage | 1111 | - |
dc.relation.volume | 25 | - |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.identifier.ulpgc | Sí | es |
dc.description.sjr | 0,506 | |
dc.description.jcr | 0,835 | |
dc.description.sjrq | Q3 | |
dc.description.jcrq | Q4 | |
dc.description.scie | SCIE | |
item.fulltext | Sin texto completo | - |
item.grantfulltext | none | - |
crisitem.author.dept | Departamento de Ciencias Médicas y Quirúrgicas | - |
crisitem.author.fullName | Martínez Quintana, Efrén | - |
Colección: | Artículos |
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