Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/43363
Title: Fat embolism secondary to yellow fat disease in an Appaloosa horse
Authors: Suarez Bonnet, Alejandro 
Espinosa de los Monteros y Zayas, Antonio 
Herráez Thomas, Pedro Manuel 
Rodríguez Guisado, Francisco 
Andrada Borzollino, Marisa Ana 
Caballero Cansino, María José 
UNESCO Clasification: 310907 Patología
Keywords: Fat embolism
Horses
Nutritional panniculitis
Yellow fat disease
Issue Date: 2008
Publisher: 1040-6387
Journal: Journal of Veterinary Diagnostic Investigation 
Abstract: A 4-year-old female Appaloosa horse was referred to the Department of Comparative Pathology, Veterinary Faculty, with a history of colic and acute respiratory distress. At necropsy, gross lesions consisted of extensive firm, multinodular, hemorrhagic foci in fat tissues with yellow-brown discoloration. The most affected areas were peritoneal fat and perirenal, epicardial, and subcutaneous adipose tissues. Other findings were hepatic lipidosis and multiple 1-1.5 cm hemorrhagic foci scattered in both lungs. Histopathological examination revealed severe degeneration and necrosis of adipose tissue with dystrophic calcification. The necrotic fat was infiltrated by abundant foamy macrophages and multinucleated giant cells. Based on these histopathological changes, yellow fat disease, also called nutritional panniculitis, was diagnosed. In addition, the microscopic examination of lung and kidney sections stained with osmium tetroxide and oil red O revealed numerous lipid droplets within glomerular and alveolar septal capillaries. To the authors' knowledge, this is the first description of the development of fat embolism in horses affected by yellow fat disease.
URI: http://hdl.handle.net/10553/43363
ISSN: 1040-6387
DOI: 10.1177/104063870802000531
Source: Journal Of Veterinary Diagnostic Investigation [ISSN 1040-6387], v. 20 (5), p. 684-687
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